TRPP2 dysfunction decreases ATP-evoked calcium, induces cell aggregation and stimulates proliferation in T lymphocytes

Autosomal dominant polycystic kidney disease (ADPKD) is mainly characterised by the development and enlargement of renal cysts that lead to end-stage renal disease (ESRD) in adult patients. Other clinical mani...

Source: BMC Nephrology - September 13, 2019 Category: Urology & Nephrology Authors: Riccardo Magistroni, Alessandra Mangolini, Sonia Guzzo, Francesca Testa, Mario R. Rapan à, Renzo Mignani, Giorgia Russo, Francesco di Virgilio and Gianluca Aguiari Tags: Research article Source Type: research