Dual T-cell Depletion with ATG and PTCy Results in Low Rates of Cytokine Release Syndrome in Peripheral Blood Haplo-HSCT

Increasing experience with Haplo-HSCT has brought attention to unique toxicities that may be less common with other modalities of transplantation such as cytokine release syndrome (CRS) [1 –3]. We read with interest the study of Dr. Imus et al. [4]. The authors report a large retrospective experience on cytokine release syndrome (CRS) after haplo-HSCT using peripheral blood (PB) allografts and post-transplant cyclophosphamide (PTCy) for graft-versus-host disease (GVHD) prophylaxis [ 4].

Source: Biology of Blood and Marrow Transplantation - September 13, 2019 Category: Hematology Authors: Maria Queralt Salas, Wilson Lam, Zeyad Al-Shaibani, Auro Viswabandya, Arjun D. Law Source Type: research