Nitrite pharmacokinetics, safety and efficacy after experimental ventricular fibrillation cardiac arrest

ConclusionsNitrite, administered early after ROSC from VF, was shown to cross the blood brain barrier after a 5 min VF cardiac arrest. We characterized the PK of intravenous nitrite administration after VF and were able to demonstrate nitrite safety in this feasibility study.
Source: Nitric Oxide - Category: Chemistry Source Type: research