Low ambient temperature as the only meteorological risk factor of seizure occurrence: A multivariate study

Publication date: November 2019Source: Epilepsy &Behavior, Volume 100, Part AAuthor(s): Kai-Chieh Chang, Tzy-Haw Wu, Jean Ching-Yuan Fann, Sam Li- sheng Chen, Amy Ming-Fang Yen, Sherry Yueh-Hsia Chiu, Fei-Chi Liu, Hsiu-Hsi Chen, Horng Huei LiouAbstractBackgroundThe onset of epileptic seizures is influenced by weather, which is multifactorial. It is unknown which specific weather factors affect the occurrence of seizures.ObjectivesWe studied the correlation between the onset of epileptic seizures and multiple weather parameters based on a population-based registry profile.MethodsWe determined the number of patients who visited emergency services in Taiwan diagnosed as having epilepsy. Then we used a linear regression model to analyze the monthly average number of patients who received emergency treatment for epilepsy in relation to temperature, barometric pressure, accumulated precipitation, relative humidity, and hours of sunshine. The Poisson regression model was used to analyze multiple meteorological factors in relation to the number of daily emergency visits because of epilepsy. A receiver operating characteristic curve was used to determine the cutoff temperature for the occurrence of seizures.ResultsTemperature appeared to be the robust factor for the onset of epilepsy. For every 1 °C decrease in temperature, there was a relative risk increase of 1.016 in the number of emergency visits as a result of epilepsy. Temperature lower than 18 °C had the best pr...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research

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DiscussionA common procedure for assessing cognitive and psychobehavioral function is now available in patients with epilepsy undergoing surgical evaluation have been established, they may help to improve the quality of care and the patient experience. This work highlights the need of furthers investigations and the necessity to develop specific tools with normative data.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Publication date: Available online 16 October 2019Source: Epilepsy &BehaviorAuthor(s): Giada Pauletto, Francesco Bax, Gian Luigi Gigli, Simone Lorenzut, Lorenzo Verriello, Elisa Corazza, Mariarosaria ValenteAbstractAim of the studyThe aim of the study was to evaluate the clinical characteristics of patients with previous stroke (either ischemic or hemorrhagic), who developed status epilepticus (SE) mimicking a stroke relapse.Materials and methodsWe performed a retrospective cohort study of patients brought to hospital by the emergency service between December 2016 and January 2018 with a stroke code as possible candida...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Publication date: Available online 15 October 2019Source: Pharmacology &TherapeuticsAuthor(s): Theresa Auer, Philipp Schreppel, Thomas Erker, Christoph SchwarzerAbstractEpilepsies represent one of the most common neurological diseases worldwide. They are characterized by recurrent spontaneous seizures with severe impact on a patient’s life. An imbalance in excitatory and inhibitory signalling is considered the main underlying pathophysiological mechanism. Therefore, GABA-mimetic drugs, strengthening the main inhibitory signalling system in the CNS, are frequently used as antiepileptic or anticonvulsant drugs. How...
Source: Pharmacology and Therapeutics - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 15 October 2019Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Carmen De Caro, Luigi Francesco Iannone, Rita Citraro, Pasquale Striano, Giovambattista De Sarro, Andrew Constanti, John F. Cryan, Emilio RussoAbstractThe gut-microbiota, the complex intestinal microbial ecosystem essential to health, is an emerging concept in medicine. Several studies demonstrate a microbiota-gut-brain bidirectional connection via neural, endocrine, metabolic and immune pathways. Accordingly, the gut microbiota has a crucial role in modulating intestinal permeability, to alter local/peripheral immun...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
Genes, Vol. 10, Pages 816: TRIM39-RPP21 Variants (∆19InsCCC) Are Not Associated with Juvenile Idiopathic Epilepsy in Egyptian Arabian Horses Genes doi: 10.3390/genes10100816 Authors: Victor N. Rivas Monica Aleman Janel A. Peterson Anna R. Dahlgren Erin N. Hales Carrie J. Finno Juvenile idiopathic epilepsy (JIE) is an inherited disease characterized by recurrent seizures during the first year of life in Egyptian Arabian horses. Definitive diagnosis requires an electroencephalogram (EEG) performed by a veterinary specialist. A recent study has suggested that a 19 base-pair deletion, along with a triple-C ...
Source: Genes - Category: Genetics & Stem Cells Authors: Tags: Brief Report Source Type: research
Gluten-related disorders (GRDs) are a group of immune-mediated diseases with several clinical manifestations triggered by gluten ingestion (1). The three main forms of GRDs are celiac disease (CD), wheat allergy (WA) and non-celiac gluten-sensitivity (NCGS) [1,2]. GRDs often present extraintestinal symptoms. Neurological manifestations have been reported in 10 to 22% of patients with coeliac disease (CD) and include gluten ataxia, polyneuropathy, myopathy, epilepsy, leukoencephalopathy, and headache [3].
Source: Seizure: European Journal of Epilepsy - Category: Neurology Authors: Source Type: research
We report the case of a 42-year-old female, diagnosed with major depressive disorder (recurrent) and psychogenic non epileptic seizures (PNES), who showed TEAS with intermittent theta burst stimulation (iTBS). She presented with an episode of low mood, vague pain symptoms such as headache, reduced interest, easy fatigability, disturbed sleep and impaired activities of daily living for one month.
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - Category: Neurology Authors: Source Type: research
Population growth fuelling environmental crisis – but nearly half of pregnancies globally are unintended Related items fromOnMedica HPV programme linked to dramatic fall in cervical disease Most CCGs missing smoking target for pregnant women Should we have compulsory measles vaccination at school entry? Should we recognise obesity as a disease? Tool helps GPs predict risk of epilepsy seizures in pregnancy
Source: OnMedica Latest News - Category: UK Health Source Type: news
Is it fair to let athletes with naturally higher testosterone compete as females without reducing their hormonal levels? Related items fromOnMedica MHRA tightens licence restrictions on valproate for women Hunt announces Medicines and Medical Devices Safety Review Include pregnant women in studies, urge researchers Tool helps GPs predict risk of epilepsy seizures in pregnancy Too few women take part in many CVD clinical trials
Source: OnMedica Latest News - Category: UK Health Source Type: news
Epileptic brain tissue is often considered physiologically dysfunctional, and the optimal treatment of many patients with uncontrollable seizures involves surgical removal of the epileptic tissue. However, it is unclear to what extent the epileptic tissue is capable of generating physiological responses to cognitive stimuli and how cognitive deficits ensuing surgical resections can be determined using state-of-the-art computational methods. To address these unknowns, we recruited six patients with nonlesional epilepsies and identified the epileptic focus in each patient with intracranial electrophysiological monitoring. We...
Source: Science Translational Medicine - Category: Biomedical Science Authors: Tags: Research Articles Source Type: research
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