Isolation and antimacrofouling activity of indole and furoquinoline alkaloids from 'guatamb ú' trees (Aspidosperma australe and Balfourodendron riedelianum).

Isolation and antimacrofouling activity of indole and furoquinoline alkaloids from 'guatambú' trees (Aspidosperma australe and Balfourodendron riedelianum). Chem Biodivers. 2019 Sep 13;: Authors: Pérez M, Pis Diez CM, Valdez MB, García M, Paola A, Avigliano E, Palermo JA, Blustein G Abstract In this work the antifouling activity was studied of five alkaloids isolated from trees of the Atlantic rainforest. The tested alkaloids were: olivacine ( 1 ), uleine ( 2 ) and N -methyltetrahydroellipticine ( 3 ) from Aspidosperma australe ('yellow guatambú') and the furoquinoline alkaloids kokusaginine ( 4 ) and flindersiamine ( 5 ) from Balfourodendron riedelianum ('white guatambú'). All these compounds can be isolated from their natural sources in high yields in a sustainable way. The five compounds were subjected to laboratory tests (attachment test of the mussel Mytilus edulis platensis ) and field trials, by incorporation into soluble matrix paints, and 45 days of exposure of the painted panels in the sea. The results show that compound 3 is a very potent antifoulant, and that compounds 4 and 5 are also very active, while compounds 1 and 2 did not show any significant antifouling activity. These results open the way for the development of environmentally friendly antifouling agents, based on abundant and easy-to-purify compounds that can be obtained in a sustainable way. PMID: 31515922 [PubMed - as supplied by publisher]
Source: Chemistry and Biodiversity - Category: Biochemistry Authors: Tags: Chem Biodivers Source Type: research