The association between 18F-fluorodeoxyglucose PET intratumoral metabolic heterogeneity and pathological parameters in non-small cell lung cancer

Objective The aim of this study was to evaluate the association between intratumoral metabolic heterogeneity on 18F-fluorodeoxyglucose (18F-FDG) PET imaging and the pathological type, differentiation and T stage of non-small cell lung cancer (NSCLC). Methods Two hundred thirty-four consecutive patients who were performed pretreatment 18F-FDG PET/computed tomography and pathologically diagnosed as NSCLC were assessed retrospectively. Metabolic heterogeneity factor (MHF) derived from the volume-threshold function from 40 to 90% was calculated for primary lesions. The association between MHF and the pathological type, differentiation and T stage of NSCLC were analyzed, respectively. Results The MHF values were statistically different among pathological types, differentiation and T stages (F = 17.611, 23.932 and 11.082, P all 
Source: Nuclear Medicine Communications - Category: Nuclear Medicine Tags: Original Articles Source Type: research