Ethnopharmacology, phytochemistry and biological activity of Erodium species: A review

The objective of this review was to show the recent and relevant studies about extraction of bioactive compounds, the phytochemical characterization, the potential biological activities and toxicological evidence reported in both in vitro and in vivo studies from Erodium spp. In addition, the use of Erodium spp. as natural compounds against the development of diseases were also showed. This review highlights the traditional use of Erodium species in several countries as a therapeutic agent to treat several diseases (such as constipation, dermatological disorders, diabetes, indigestion, urinary inflammations, and as carminative agent), the factors influencing the extraction of bioactive compounds (mainly species and solvent composition on phenolic compounds) and phytochemical profile (presence of essential oils and alkaloids), the scientific evidence about its anti-inflammatory, antimicrobial (against both spoilage and pathogenic microorganisms), antiviral and other health-related activities (anti-protozoal and anti-viral activity) as well as the toxicological evidence. Erodium spp. is a relevant source of compounds with antioxidant, antimicrobial, and biological activity, which support its potential exploration in pharmacological and food area. Major efforts are necessary to advance the knowledge about Erodium genus regarding the relation between traditional use and scientific evidence, optimization of extraction conditions, the influence on biological mechanisms at animal an...
Source: Food Research International - Category: Food Science Source Type: research

Related Links:

This study aimed to investigate the one-month outcome of patients with unspecified abdominal pain. Methods: This cohort study was conducted on subjects who were evaluated in ED with unspecified abdominal pain and were referred to the gastroenterology clinic and followed for one month. Finally, they were divided into two groups of cases with clear cause of abdominal pain and unclear cause of abdominal pain and patients' characteristics were compared between the groups. Results: 150 cases with the mean age of 40.68 ± 18.34 years were studied (53.3% female). After one month, 67 (44.7%) patients still complain...
Source: Accident and Emergency Nursing - Category: Emergency Medicine Authors: Tags: Arch Acad Emerg Med Source Type: research
Publication date: Available online 13 October 2019Source: Life SciencesAuthor(s): Yu-Chieh Chen, Jiunn-Ming Sheen, Mei-Hsin Hsu, Chih-Cheng Hsiao, Su-Chen Wang, Li-Tung HuangAbstractAimsWith the improvement of the survival rates in children acute lymphoblastic leukemia (ALL), some children ALL survivors show impaired cognitive function. Methotrexate (MTX), an essential component in ALL treatment, has been reported to be related to neurologic sequelae and to increased oxidative stress through its interactions with enzymes in the folate pathway. Asymmetric dimethylarginine (ADMA) is the main endogenous inhibitor of nitric ox...
Source: Life Sciences - Category: Biology Source Type: research
This study aims to explore the role of lncRNAs in the glucometabolic action of metformin on skeletal muscle cells.Main methodsMetformin accumulation was assessed using [14C]-metformin. A lncRNA array was used to investigate metformin-regulated lncRNAs in C2C12 skeletal muscle cells. Knockdown studies were applied to evaluate the function of lncRNA Dreh. A colorimetric assay was used for the measurement of medium glucose concentration; glucose transport was assessed using [3H]-2-deoxyglucose; real-time PCR was used for RNA expression analysis, and western blotting was used to assess protein expression in myotubes. A Dreh ov...
Source: Life Sciences - Category: Biology Source Type: research
Publication date: Available online 12 October 2019Source: The Journal of Supercritical FluidsAuthor(s): Rosario Goyeneche, Karina Di Scala, Cristina L. Ramirez, María A. FanovichAbstractSupercritical fluid extraction by using CO2 can be employed as an alternative to conventional methods for extracting functional compounds from vegetable leaves. Overall extractions curves of bioactive compounds from beetroot leaves were performed using scCO2 with ethanol as co-solvent. Yield, total phenolic compounds and antioxidant activity were determined for each extract. The best results were obtained at 35 °C/400&thin...
Source: The Journal of Supercritical Fluids - Category: Chemistry Source Type: research
ConclusionsThe in vitro studies and in vivo models have provided a simple bio-scientific justification for various ethnopharmacological uses of Psoralea species. From the toxicological perspective, the root, leaf, and seed extracts and their preparations have been proven to be safe when consumed in the recommended doses. But, meticulous studies on the pharmaceutical standardization, mode of action of the active constituents, and sustainable conservation of Psoralea species are needed, to meet the growing demands of the pharmaceutical industries, and to fully exploit their preventive and therapeutic potentials.
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
ConclusionsThe in vitro studies and in vivo models have provided a simple bio-scientific justification for various ethnopharmacological uses of Psoralea species. From the toxicological perspective, the root, leaf, and seed extracts and their preparations have been proven to be safe when consumed in the recommended doses. But, meticulous studies on the pharmaceutical standardization, mode of action of the active constituents, and sustainable conservation of Psoralea species are needed, to meet the growing demands of the pharmaceutical industries, and to fully exploit their preventive and therapeutic potentials.
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
hunpeng Wan Medicinal plants have served humans since prehistoric times to treat various ailments. Both developed and underdeveloped countries rely on traditional systems of medication using natural sources from plants. Phyllanthus is one of the largest genus in the family Phyllanthaceae, comprising over 700 well known species cosmopolitan in distribution mainly in the tropics and subtropics. Phyllanthus species are being in constant used in traditional medications to cure an array of human diseases (constipation, inhalation related, arthritis, loss of appetite, injuries, conjunctivitis, diarrhoea, running nose, common...
Source: Molecules - Category: Chemistry Authors: Tags: Review Source Type: research
When I was traveling in India, I had the privilege of studying Ayurvedic medicine with traditional Master Healers. Surrounded by lakes, oceans and mountains, Kerala, India, is the birthplace of Ayurveda medicine. My plane landed in Mumbai. From there, I made the 800-mile trip to Kerala down on the southwestern-most tip of the Indian peninsula. With origins dating back 6,000 years, Kerala is the birthplace of Ayurvedic medicine. I spent a lot of time at the AyurMana or “ancient healing house.” This is the oldest existing school of Ayurvedic medicine in the world. It was there that I observed how quickly...
Source: Al Sears, MD Natural Remedies - Category: Complementary Medicine Authors: Tags: Health Natural Cures anxiety arthritis Cancer celiac disease chronic fatigue depression diabetes digestive issues fibromyalgia leaky gut multiple sclerosis schizophrenia Source Type: news
Authors: Park S, Park SY, Kim YJ, Hong SM, Chon S, Oh S, Woo JT, Kim SW, Kim YS, Rhee SY Abstract BACKGROUND: Gastrointestinal (GI) symptoms are common in patients with type 2 diabetes mellitus (T2DM). Rebamipide is an effective gastric cytoprotective agent, but there are few data on its usefulness in T2DM. The aim of this study is to evaluate the improvement of GI symptoms after rebamipide treatment in patients with T2DM. METHODS: Patients with T2DM and atypical GI symptoms were enrolled. They took rebamipide (100 mg thrice daily) for 12 weeks and filled out the diabetes bowel symptom questionnaire (DBSQ) befo...
Source: Diabetes and Metabolism Journal - Category: Endocrinology Tags: Diabetes Metab J Source Type: research
Old age, life's last stage and an inescapable reality has become in recent years, the focus of attention in developing countries. Life expectancy has risen, leading to a sharp rise in the number of older persons. The present research work was conducted to study dietary pattern and nutritional status of retired elderly residing in an agriculture-based area of Rajasthan, India. Sixty-plus retired elderly, who were cooperative and mentally receptive, comprised the study sample. A questionnaire was designed and pre-tested to collect data on various aspects, such as general profile, nutritional status, lifestyle, and habits. Al...
Source: Advances in Nutrition - Category: Nutrition Authors: Tags: Community, Public Health, and Global Nutrition Source Type: research
More News: Antidoxidants | Constipation | Dermatology | Diabetes | Endocrinology | Food Science | Indigestion | Salads | Skin | Study | Toxicology