Phosphatase regulation of immunoreceptor signaling in T cells, B cells and mast cells.

Phosphatase regulation of immunoreceptor signaling in T cells, B cells and mast cells. Curr Opin Immunol. 2013 May 15; Authors: Bounab Y, Getahun A, Cambier JC, Daëron M Abstract Recent progress has begun to reveal the often complex and changing roles of phosphotyrosine and phosphoinositide phosphatases in regulation of immunoreceptor signaling. The resultant confusion has been further increased by discoveries of new players. Here we provide a review of recent progress in defining the roles of these enzymes in immunoreceptor-dependent mast cell, T cell and B cell activation. PMID: 23684445 [PubMed - as supplied by publisher]
Source: Current Opinion in Immunology - Category: Allergy & Immunology Authors: Tags: Curr Opin Immunol Source Type: research