Evolving therapeutic goals in ulcerative colitis: towards disease clearance

Nature Reviews Gastroenterology & Hepatology, Published online: 13 September 2019; doi:10.1038/s41575-019-0211-1In ulcerative colitis, treating beyond endoscopic healing has shown a reduction of relapse and hospitalization, pushing for histological remission to be embraced in clinical practice and clinical trials. Here, we propose the concept of disease clearance (symptomatic, endoscopic and histological remission) as the ultimate goal in the treatment of ulcerative colitis.
Source: Nature Reviews Gastroenterology and Hepatology - Category: Gastroenterology Authors: Source Type: research