Gastroesophageal Reflux Disease and Atrial fibrillation: Insight from Autonomic Cardiogastric Neural Interaction

In this study, we investigated the effects of acid reflux on the intrinsic cardiac autonomic nervous system, atrial/ventricular electrophysiology, and AF inducibility.MethodsEighteen rabbits were randomized into three groups: acid reflux (group 1, n = 6), control (group 2, n = 6), and acid reflux with periesophageal vagal blockade (group 3, n = 6). Atrial and ventricular effective refractory periods (ERPs) and AF inducibility were checked at baseline and then hourly until 5 hours after the experiment.ResultsThree hours after the experiment, atrial ERP prolongation was noted in groups 2 and 3 (P
Source: Journal of Cardiovascular Electrophysiology - Category: Cardiology Authors: Tags: ORIGINAL ‐ EXPERIMENTAL Source Type: research

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Introduction: Obstructive sleep apnea (OSA) and chronic obstructive pulmonary (COPD), are usually accompanied by several comorbidities. Aim of the study was to assess the prevalence of comorbidities in OSA and COPD-OSA overlap syndrome (OS) patients and to explore differences between these two groups.Methods: Included were consecutive OS (n=163, 138 males, AHI>5/h and FEV1/FVC5/h and FEV1/FVC>0.7), matched in terms of gender, age, BMI, and smoking history, diagnosed with polysomnography and pulmonary function testing.Results: As mentioned, the two groups were matched in age (p=0.221), BMI (p=0.496) and neck circumfer...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Sleep and control of breathing Source Type: research
CONCLUSIONS: this meta-analysis supported the association of AF with increased risk of GERD. PMID: 31617365 [PubMed - as supplied by publisher]
Source: Revista Espanola de Enfermedades Digestivas - Category: Gastroenterology Tags: Rev Esp Enferm Dig Source Type: research
A 71-YEAR-OLD, 67 kg, 170 cm man presented to the authors ’ institution for evaluation of atypical chest pain of 6 months duration. The patient described his chest discomfort as relatively mild. It seldomly persisted for more than a few seconds; was confined to the left chest without radiation; and was not related to activity, position, or breathing. He denied dysphagia, odynophagia, and symptoms of gastroesophageal reflux disease. The patient had a history of chronic atrial fibrillation and peripheral vascular disease for which he received chronic dual antiplatelet therapy (apixaban and clopidogrel).
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Diagnostic Dilemma Source Type: research
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Source: Journal of Cardiovascular Electrophysiology - Category: Cardiology Authors: Tags: EDITORIAL – INVITED Source Type: research
We report on such a case in which a patient was found to be hyponatremic after evaluation. An 88-year-old male who presented to the emergency department was found to be hyponatremic secondary to amiodarone-induced SIADH following a fall, with possible seizure and traumatic brain injury. He had a history of hypertension, paroxysmal atrial fibrillation, emphysema, myocardial infarction, benign prostatic hyperplasia, chronic kidney disease, Meniere's disease, anemia, and gastroesophageal reflux. Upon admission, his urine sodium level was elevated, and his serum sodium, urine osmolality, and anion gap were below normal. In the...
Source: P and T - Category: Drugs & Pharmacology Tags: P T Source Type: research
We present an economic evaluation of a recently completed cohort study in which 2054 seniors were screened for atrial fibrillation (AF) in 22 Canadian family practices. Using a Markov model, trial and literature data were used to project long-term outcomes and costs associated with 4 AF screening strategies for individuals aged 65 years or older: no screening, screen with 30-second radial manual pulse check (pulse check), screen with a blood pressure machine with AF detection (BP-AF), and screen with a single-lead electrocardiogram (SL-ECG). Costs and outcomes were discounted at 1.5% and the model used a lifetime horizon f...
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
We present an economic evaluation of a recently completed cohort study which screened 2,054 seniors for atrial fibrillation (AF) in 22 Canadian family practices (FPs). Using a Markov model, trial and literature data were used to project long-term outcomes and costs associated with four AF screening strategies for individuals aged 65 years or older: no screening, screen with 30-s radial manual pulse check (pulse check), screen with a blood pressure machine with AF detection (BP-AF) and screen with a single-lead ECG (SL-ECG). Costs and outcomes were discounted at 1.5% and the model uses a lifetime horizon from public payer p...
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
AbstractIn a previous report of two married cohabiting couples affected by polymyalgia rheumatica (PMR), we noticed that the wife of one couple and both members of the other couple suffered from symptomatic diverticular disease (DD), whose diagnosis was made before the onset of PMR. We investigated whether DD might be a risk factor for the development of PMR. We conducted a case-control study informed on a database containing the prospectively collected medical records of consecutive PMR patients. Among comorbidities, attention was focused on symptomatic DD, provided that the diagnosis had been made by colonoscopy and/or c...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
Source: Gastroenterology - Category: Gastroenterology Authors: Tags: AGA Abstracts Source Type: research
Source: Gastroenterology - Category: Gastroenterology Authors: Tags: AGA Abstracts Source Type: research
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