E6 and E7 gene polymorphisms in human papillomavirus Type-6 identified in Southwest China

Human papillomavirus type-6 (HPV6) is the major etiological agent of anogenital warts both men and women. The present study aimed to characterize the genetic diversity among HPV6 in Southwest China, and to inv...
Source: Virology Journal - Category: Virology Authors: Tags: Research Source Type: research

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Conclusion: Oral isotretinoin is superior to placebo for treating mucocutaneous human papillomavirus infections, particularly plane warts. The recurrence rate and risk of severe side effects are low.
Source: Indian Journal of Dermatology, Venereology and Leprology - Category: Dermatology Authors: Source Type: research
This study estimated genital warts prevalence, genital-warts-related healthcare resource use and costs, and self-reported human-papillomavirus-related psychosocial impact among male and female patients aged 18...
Source: Infectious Agents and Cancer - Category: Cancer & Oncology Authors: Tags: Research Article Source Type: research
Abstract Warts are benign neoplasms of the skin and mucosa caused by human papillomavirus (HPV) infection.1 The most common treatments for wart are topical application of salicylic acid and cryotherapy. Other modalities include chemical agents, contact sensitizing agents and surgical excision.2 Laser modalities, including carbon dioxide (CO2 ), pulsed dye and neodymium-doped: yttrium-aluminum-garnet lasers, have also been used to treat recalcitrant plantar warts. PMID: 31545511 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - Category: Dermatology Authors: Tags: Br J Dermatol Source Type: research
Conclusions: MBL play an important role in host defense against HPV infection. PMID: 31469597 [PubMed - as supplied by publisher]
Source: Journal of Dermatological Treatment - Category: Dermatology Tags: J Dermatolog Treat Source Type: research
Human papillomavirus (HPV) presents tropism for the skin and mucous membranes and produces a variety of afflictions. There are available many studies on the role of oxidative stress in HPV-associated cervical cancer; however data on cutaneous lesions is scarce. In recent years, it has been highlighted that lipid peroxidation is an important step in the pathogenesis of many diseases. We have enrolled 26 patients with palmoplantar warts, 15 patients with genital warts and 28 healthy subjects. To determine the level of lipid peroxidation we have measured the serum levels of 4-hydroxynonenal (4-HNE) by ELISA method.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Clinical Research and Epidemiology Source Type: research
Genital human papilloma virus (HPV) infection is the most common sexually transmitted infection. It may be asymptomatic or manifests as benign or malignant lesions. The pathogenesis of HPV infection is not completely elucidated; in most cases spontaneous viral clearance occurs. In our study we have investigated the effect of HPV infection on the balance between oxidants and antioxidants in patients with genital warts. We have determined the serum levels of soluble receptor for advanced glycation end products (sRAGE), total oxidant status (TAS) and total antioxidant status (TOS) in 15 patients with genital warts and 28 healthy subjects.
Source: Journal of Investigative Dermatology - Category: Dermatology Authors: Tags: Innate Immunity and Inflammation Source Type: research
AbstractIn the U.S. there is an epidemic of sexually transmitted diseases (STIs). One of the most prevalent STIs is the Human Papillomavirus (HPV). Certain high risk strains of HPV are believed to cause virtually all cervical cancers, over 90% of anal cancers, 70% of oropharyngeal cancers, and the majority of anal  genital warts. HPV is preventable through vaccination and is available for both men and women. Several educational interventions have been employed, yet baseline awareness and knowledge related to HPV and 9vHPV remains relatively low among young men. What is not known is the most effective method for provid...
Source: Journal of Community Health - Category: International Medicine & Public Health Source Type: research
Abstract Human papillomavirus (HPV) causes nearly all cervical cancers and some cancers of the vagina, vulva, penis, anus, and oropharynx (1).* Most HPV infections are asymptomatic and clear spontaneously within 1 to 2 years; however, persistent infection with oncogenic HPV types can lead to development of precancer or cancer (2). In the United States, the 9-valent HPV vaccine (9vHPV) is available to protect against oncogenic HPV types 16, 18, 31, 33, 45, 52, and 58 as well as nononcogenic types 6 and 11 that cause genital warts. CDC analyzed data from the U.S. Cancer Statistics (USCS)† to assess the incide...
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
Background: Verruca vulgaris (common warts) is a cutaneous manifestation of the human papillomavirus that impacts children and adults. Effective treatment is challenging as no FDA-approved therapies are available. We evaluated the efficacy and safety of the proprietary, stabilized hydrogen peroxide topical solution, 45% (w/w) (HP45) in patients with common warts.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
Background: Verruca vulgaris (common warts) is a cutaneous manifestation of the human papillomavirus with no FDA-approved therapies available. We evaluated the long-term efficacy and safety of the proprietary, stabilized hydrogen peroxide topical solution, 45% (w/w) (HP45) in patients with common warts at 12 weeks after treatment completion.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Source Type: research
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