Herpes simplex virus type 1 suppresses the transformed phenotype of cultured cells.

Herpes simplex virus type 1 suppresses the transformed phenotype of cultured cells. Acta Virol. 2019;63(3):338-400 Authors: Búda D, Mrázová V, Šupolíková M, Golais F PMID: 31507202 [PubMed - in process]
Source: Acta Virologica - Category: Infectious Diseases Authors: Tags: Acta Virol Source Type: research

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ConclusionsExperimental investigation showed promising antiviral, antibacterial, and/or anti-inflammatory activities of the phenolic mulberry constituents, often with multiple inhibitory effects that might be used as a potential source of new medicine.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
Larabell Vihinen-Ranta During lytic herpes simplex virus 1 (HSV-1) infection, the expansion of the viral replication compartments leads to an enrichment of the host chromatin in the peripheral nucleoplasm. We have shown previously that HSV-1 infection induces the formation of channels through the compacted peripheral chromatin. Here, we used three-dimensional confocal and expansion microscopy, soft X-ray tomography, electron microscopy, and random walk simulations to analyze the kinetics of host chromatin redistribution and capsid localization relative to their egress site at the nuclear envelope. Our data demon...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
Viral Immunology, Ahead of Print.
Source: Viral Immunology - Category: Allergy & Immunology Authors: Source Type: research
We report a rare case of esophageal perforation with penetration into vertebral space secondary to chronic HSV esophagitis in a 71-year-old immunocompetent female. This is the second known such occurrence. The patient had a long stay in hospital but recovered from the condition and was followed up for one year after initial presentation. PMID: 31604094 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Ann Thorac Surg Source Type: research
-- Herpes is a common and usually mild skin condition caused by the herpes simplex virus (HSV). If you are living with herpes, Sutter Health encourages you to: Be alert to triggers that activate herpes. Use safe sex methods, such as...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
This study aimed to evaluate the antiviral activity of C. gileadensis as well as to isolate its active compound and investigate its mode of action. This activity was evaluated using 4 viruses, herpes simplex virus type 2 (HSV-2), respiratory syncytial virus type B (RSV-B), coxsackie virus B type 3, and adenovirus type 5 by performing the plaque reduction assay and the 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assays for enveloped and nonenveloped viruses, respectively. The methanol extract of C. gileadensis leaves only showed antiviral activity against enveloped viruses with a selectivity index of 11.19 ...
Source: Planta Medica - Category: Drugs & Pharmacology Authors: Tags: Original Papers Source Type: research
Conjoined twins are an exceptionally rare phenomenon caused by partial separation of an early embryo after the twelfth day of fertilization. In this article we are reporting a case of conjoined twins diagnosed in our department. During a examination in the XXI week of gestation, a 24 years old woman, with the presence of labial herpes simplex following an ultrasound examination was suspected of carrying conjoined twins. To confirm, we performed prenatal Magnetic Resonance Imaging (MRI), which proved the existence of cephalothoracoomphalopagus.
Source: Radiography - Category: Radiology Authors: Tags: Case report Source Type: research
Purpose of review To review ocular manifestations and complications of herpes simplex virus (HSV) and discuss recent advancements in diagnostic and treatment strategy. Recent findings In-vivo confocal microscopy has expanded our understanding of corneal nerve degeneration, corneal dendritic cell activity, and changes in biomechanical properties in HSV keratitis. Although currently available only as a research tool, metagenomic deep sequencing has the potential to improve diagnostic accuracy beyond the well established PCR technology, especially in atypical cases. Development of an HSV vaccine has shown some encouragin...
Source: Current Opinion in Ophthalmology - Category: Opthalmology Tags: OCULAR MANIFESTATIONS OF SYSTEMIC DISEASE: Edited by John A. Gonzales Source Type: research
This article will provide a thorough review of radiologic findings in common infections of the brain, from primarily compartmentalized infections of multi-microbial etiologies, to CNS manifestations of specific immunocompromised-selective pathogens, of herpes simplex virus (HSV), and of tuberculosis. We also briefly discuss the epidemiology, etiology, clinical features, treatment guidelines, complications, and long-term sequelae of these infections.
Source: Seminars in Ultrasound, CT and MRI - Category: Radiology Source Type: research
In this study, we aim to analyze the current evidence and findings associated with influenza and other emergent viral infections, namely, herpes simplex virus type 1 (HSV-1), Epstein-Barr virus (EBV), and cytomegalovirus (CMV).Among medical conditions, community-acquired respiratory infections are the most frequent reason for ventilatory support in ICUs. Community-acquired pneumonia in a severe form including the need of invasive mechanical ventilation and/or vasopressors is associated with high mortality rates. However, after the pandemic that occurred in 2009 by H1N1 influenza, the number of cases being admitted to ICUs ...
Source: Seminars in Respiratory and Critical Care Medicine - Category: Respiratory Medicine Authors: Tags: Review Article Source Type: research
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