GCT-08 - Ovarian and testicular malignant teratomas: A comparative pathological analysis

Publication date: 2019Source: European Urology Supplements, Volume 18, Issue 4Author(s): A.A. Hadjiconstanti, B.M.R. Mathew, C.A. Freeman, D.R. Arora, E.M. Lockley
Source: European Urology Supplements - Category: Urology & Nephrology Source Type: research

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We present this case for the uniqueness of the bilateral ovarian pathology as well as to show that robotic-assisted resection of ovarian tumors in certain children is safe and feasible.
Source: Journal of Pediatric Surgery Case Reports - Category: Surgery Source Type: research
CONCLUSIONS: Primary ovarian SCC is a rare entity with poor prognosis, compared to serous carcinoma. Treatment is usually extrapolated from classical ovarian carcinoma algorithms, including surgical management combined with adjuvant chemotherapy with or without radiotherapy. Further investigations are needed to define optimal treatment, such as chemotherapy regimens and the role of radiotherapy and lymph node dissection. PMID: 31786837 [PubMed - in process]
Source: Journal of B.U.ON. - Category: Cancer & Oncology Tags: J BUON Source Type: research
Ovarian mature cystic teratomas comprise tissues derived from all three germ layers. In rare incidences, malignant tumors may arise from ovarian mature cystic teratoma, which occurs in 0.2 –1.8% of cases. A var...
Source: BMC Women's Health - Category: OBGYN Authors: Tags: Case report Source Type: research
This review describes the germ cell neoplasms that are malignant and most commonly associated with several types of gonadal dysgenesis. The most common neoplasm is gonadoblastoma, while others including dysgerminomas, yolk-sac tumors and teratomas are rare but can occur. The purpose of this review is to evaluate the incidences of these abnormalities and the circumstances surrounding these specific tumors. According to well-established methods, a PubMed systematic review was performed, to obtain relevant studies published in English and select those with the highest-quality data. Initially, the first search was performed us...
Source: Clinics - Category: General Medicine Source Type: research
Abstract Although mature cystic teratoma (MCT) is benign, malignant transformation (MT) occurs in ~ 1% to 2% of all cases, and usually consists of squamous cell carcinoma (SCC), which accounts for ~ 80% of the cases. Spindle-cell (sarcomatoid) carcinoma (SCSC) is an uncommon type of SCC, comprising up to 3% of all cases. The lack of characteristic symptoms and specific imaging findings may lead to preoperative misdiagnosis. Moreover, the clinicopathologic characteristics, the treatment, the prognostic factors and the mechanism of MT have not yet been well understood due to the rarity of such tumors, especially in women of ...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
A 44-year-old woman presented to the colorectal surgeons with a six month history of tenesmus and change in bowel habit. Initial investigations suggested a malignant colorectal tumour but biopsies showed squamous metaplasia and no colonic tissue. After further investigation and discussion at multiple multidisciplinary meetings, surgical resection of a large pelvic mass including sigmoid colon, uterus and ovary was performed. Histological examination of this mass showed intra-colonic polypoid endometriosis with fistulation through into an adjacent large cystic space, which was found to be a mature cystic teratoma.
Source: Diagnostic Histopathology - Category: Pathology Authors: Tags: Mini-symposium: Short case Source Type: research
Conclusions Patients in China present with psychosis and seizure frequently but have a low percentage of underlying neoplasms. Re-enforced first-line immunotherapy is effective in managing anti-NMDAR encephalitis in the acute phase. Although relapse is relatively common, with combined first-line and long-term immunotherapy, most patients reached favorable outcomes.
Source: Neurology Neuroimmunology and Neuroinflammation - Category: Neurology Authors: Tags: Autoimmune diseases, All Clinical Neurology Article Source Type: research
We describe a case of successful in vitro fertilization pregnancy and delivery after a fertility-sparing laparoscopic operation in a patient with papillary thyroid carcinoma arising from a mature cystic teratoma. PMID: 31401818 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Reproductive Medicine - Category: Reproduction Medicine Tags: Clin Exp Reprod Med Source Type: research
Tumor-to-tumor metastasis (TTM) is a rare but well-documented phenomenon that is defined as metastasis in a histologically distinct tumor. Ovarian mature teratomas (OMTs) can coexist with various cancers by ma...
Source: Diagnostic Pathology - Category: Pathology Authors: Tags: Case Report Source Type: research
Authors: Abstract Adnexal torsion is the fifth most common gynecologic emergency. The most common ovarian pathologies found in adolescents with adnexal torsion are benign functional ovarian cysts and benign teratomas. Torsion of malignant ovarian masses in this population is rare. In contrast to adnexal torsion in adults, adnexal torsion in pediatric and adolescent females involves an ovary without an associated mass or cyst in as many as 46% of cases. The most common clinical symptom of torsion is sudden-onset abdominal pain that is intermittent, nonradiating, and associated with nausea and vomiting. If ovarian ...
Source: Obstetrics and Gynecology - Category: OBGYN Tags: Obstet Gynecol Source Type: research
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