Biomarkers of Intestinal Fibrosis in Small Bowel Crohn's Disease

Condition:   Crohn Disease Interventions:   Diagnostic Test: blood biomarkers;   Diagnostic Test: stool biomarkers;   Diagnostic Test: MRI imaging Sponsors:   Children's Hospital Medical Center, Cincinnati;   The Leona M. and Harry B. Helmsley Charitable Trust Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Authors: Mahamid M, Bar-Gil Shitrit A, Amara H, Koslowsky B, Ghantous R, Safadi R Abstract BACKGROUND: Crohn's disease and ulcerative colitis are the two major classic presentations of inflammatory bowel diseases (IBD). Studies have shown a wide variation in the incidence and prevalence attributed to different geographic and ethnic populations. OBJECTIVES: To assess the clinical characteristics of IBD among Arabs in Israel and to compare them to characteristics of IBD among Ashkenazi Jews. METHODS: This retrospective, comparative study compared the clinical characteristics of IBD among 150 Arabs from the Ho...
Source: The Israel Medical Association Journal - Category: General Medicine Tags: Isr Med Assoc J Source Type: research
Purpose of review Recent knowledge teaches us that food is one of the most important environmental factors affecting our health from disease prevention to cause. Food is one of the key players in the normal gut microenvironment, affecting microbial composition, function, gut barrier and host immunity. This review aims to summarize the current data on food components as regulators of intestinal inflammation, with particular focus on the inflammatory bowel diseases (IBDs). Recent findings We summarize our current understanding on nutrition as possible cause and treatment for IBD and concentrate on several food component...
Source: Current Opinion in Gastroenterology - Category: Gastroenterology Tags: IMMUNOLOGY: Edited by Alan C. Moss Source Type: research
Researchers have found that blood vessels likely contribute to the development of inflammatory bowel diseases. The finding also suggests novel treatments.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Crohn's / IBD Source Type: news
CONCLUSIONS: The overall rate of total infectious complications or intra-abdominal septic complications was not increased based on preoperative exposure to a particular class of biologic. Rates increased with combination immunosuppression of biologic therapy with corticosteroids and previous abdominal resection. See Video Abstract at http://links.lww.com/DCR/B24. BIOLÓGICOS Y COMPLICACIONES POSTOPERATORIAS DE 30 DÍAS DESPUÉS DE LAS OPERACIONES ABDOMINALES PARA LA ENFERMEDAD DE CROHN: ¿EXISTEN DIFERENCIAS EN LOS PERFILES DE SEGURIDAD?: ANTECEDENTES: La evidencia sobre la asociación d...
Source: Diseases of the Colon and Rectum - Category: Gastroenterology Tags: Original Contributions: Inflammatory Bowel Disease Source Type: research
Publication date: Available online 8 October 2019Source: Respiratory InvestigationAuthor(s): Haruki Hirakawa, Hiroki Tashiro, Koichiro Takahashi, Masahide Tanaka, Hironori Sadamatsu, Shinya Kimura, Naoko Sueoka-AraganeAbstractMesalazine is a standard therapeutic agent for the treatment of inflammatory bowel diseases. A rare case of mesalazine-induced airway obstruction documented by pulmonary function testing is reported herein. The patient had Crohn's disease and was treated with mesalazine; she subsequently developed a high fever, cough, and chest pain with centrilobular nodular shadows on chest computed tomography (CT)....
Source: Respiratory Investigation - Category: Respiratory Medicine Source Type: research
Elective abdominal surgery for inflammatory bowel disease is common. Surgery for Crohn ’s disease is not curative, and treatment must be individualized to the disease process. Surgery for ulcerative colitis generally is curative but consideration of patient-specific factors is important for staging of the procedure and determining whether ileal pouch–anal anastomosis is appropriat e.
Source: Surgical Clinics of North America - Category: Surgery Authors: Source Type: research
Conclusion The use of anti-TNF-α in pediatric CD patients within the 90 days prior to their abdominal surgery was not associated with an increased risk of 30-day postoperative complications. [...] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: European Journal of Pediatric Surgery - Category: Surgery Authors: Tags: Original Article Source Type: research
Patients in Ontario with inflammatory bowel disease (IBD), and particularly those with Crohn's disease (CD), are at risk for high exposure to ionizing radiation from abdominal computed tomography (CT) scanning, an observational study reveals.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Medscape Today News Source Type: news
Condition:   Pediatric Penetrating Crohn's Disease Intervention:   Sponsors:   University Hospital, Montpellier;   Pediatric gastroenterology service, Toulouse University Hospital: Dr Breton;   Adult gastroenterology service, Montpellier University Hospital: Dr Pineton de Chambrun;   Pediatric gastroenterology service, Montpellier University Hospital: Dr Kollen;   EP IMAD Registry: Dr Gower-Rousseau Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CONCLUSION: In this study, we demonstrate that risk factors for NAFLD and LF in the IBD population do not differ from those in the general population. PMID: 31602167 [PubMed - in process]
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Tags: World J Gastroenterol Source Type: research
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