Cognitive and Behavioral Changes in Patients Treated With Droxidopa for Neurogenic Orthostatic Hypotension: A Retrospective Review

Conclusions: Droxidopa is designed to act peripherally as a pressor agent but may also exert important central effects. We hypothesize that the cognitive and behavioral manifestations observed in the patients with orthostatic hypotension resulted from an “overdose” of key noradrenergic networks linking orbitofrontal and mesolimbic regions.
Source: Cognitive and Behavioral Neurology - Category: Neurology Tags: Original Studies Source Type: research