Cancers, Vol. 11, Pages 1362: CRISPR Loss-of-Function Screen Identifies the Hippo Signaling Pathway as the Mediator of Regorafenib Efficacy in Hepatocellular Carcinoma

In conclusion, our screen identified the Hippo signaling pathway as the mediator of regorafenib efficacy in HCC.

Source: Cancers - September 12, 2019 Category: Cancer & Oncology Authors: Shigeki Suemura Takahiro Kodama Yuta Myojin Ryoko Yamada Minoru Shigekawa Hayato Hikita Ryotaro Sakamori Tomohide Tatsumi Tetsuo Takehara Tags: Article Source Type: research