Diagnosis and clinical outcomes of extrapulmonary tuberculosis in antiretroviral therapy programmes in low- and middle-income countries: a multicohort study.

CONCLUSIONS: Diagnosis of EPTB and PTB at ART programmes in LMIC was mainly based on clinical criteria. Greater availability and usage of TB diagnostic tests would improve the diagnosis and clinical outcomes of both EPTB and PTB. PMID: 31507083 [PubMed - in process]
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research

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Condition:   Tuberculous Meningitis Interventions:   Drug: Aspirin;   Drug: Placebo of aspirin;   Drug: WHO TBM treatment;   Drug: Intensified TBM treatment Sponsors:   French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS);   European Union;   European and Developing Countries Clinical Trials Partnership (EDCTP) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
We describe demographic, socioeconomic and clinical characteristics of patients randomized to the same-day initiation arm for both studies. RESULTS AND DISCUSSION: A total of 240 and 296 participants were enrolled in Kenya and South Africa. The majority were female (59% and 64% respectively), with a median age of 35 years. In both countries, most subjects were newly diagnosed with HIV on the day of enrolment (62%, 55%), believed they already had adequate knowledge to begin ART (78%, 68%), and preferred to start ART immediately (same-day) (98% in both countries). About 40% of all patients had at least one symptom r...
Source: Journal of the International AIDS Society - Category: Infectious Diseases Tags: J Int AIDS Soc Source Type: research
Conclusion: Neurological disorders are common in HIV in Africa and the main CNS opportunistic infections result in high  mortality rates. Strategies aimed at reducing their high burden, morbidity and mortality include early HIV diagnosis and anti-retroviral therapy (ART), screening and chemoprophylaxis of main opportunistic infections, improved clinical diagnosis and management and programme strengthening.Keywords: Neurological disorders, HIV, Africa, opportunistic infections, direct HIV infection and inflammatory disorders.
Source: African Health Sciences - Category: African Health Source Type: research
BANGLADESH: Dose of Vigilance Helps Manage HIV, AIDS DHAKA, Nov 3, 2010 (IPS) - It is one of the poorest countries in the world, has a low literacy rate, and is next door to at least two countries that have a considerable portion of their respective populations with HIV and AIDS. Yet even having a large migrant population has not made Bangladesh a hot spot for HIV and AIDS. http://ipsnews.net/news.asp?idnews=53443By James ReinlUNITED NATIONS, Jul 24 2019 (IPS) The global fight against Aids is floundering amid cash shortfalls and spikes in new HIV infections among marginalised groups in developing regions, Gunilla Carlsson,...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Development & Aid Featured Global Headlines Health IPS UN: Inside the Glasshouse Regional Categories TerraViva United Nations Joint United Nations Programme on HIV/AIDS (UNAIDS) Médecins Sans Frontières (MSF) Source Type: news
Conclusion: The present survey, for the first time, provides ground-level evidence of various aspects of CNS TB as practiced by neurologists in India. The major diversity was observed in therapeutics such as the choice of antitubercular drugs, its duration, linezolid use beyond the recommended duration, and knowledge of drug resistance. The monitoring aspects of CNS TB also showed variations. The investigational aspects of CNS TB such as using TB PCR, not using CSF ADA, and regular neuroimaging revealed a good clinical practice. Other CSF parameters require uniformity. This survey thus helps to identify areas of future wor...
Source: Neurology India - Category: Neurology Authors: Source Type: research
Condition:   Tuberculosis, Meningeal Interventions:   Drug: LZD;   Drug: High dose RIF;   Drug: Standard dose RIF Sponsors:   University of California, San Francisco;   MRC/UVRI Uganda Research Unit on Aids;   London School of Hygiene and Tropical Medicine Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 009 The diagnosis of HIV is no longer fatal and the term AIDS is becoming less frequent. In many countries, people with HIV are living longer than those with diabetes. This post will hopefully teach the basics of a complex disease and demystify some of the potential diseases you need to consider in those who are severely immunosuppressed. While trying to be comprehensive this post can not be exhaustive (as you can imagine any patient with ...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Clinical Cases Tropical Medicine AIDS art cryptococcoma cryptococcus HIV HIV1 HIV2 PEP PrEP TB toxoplasma tuberculoma Source Type: blogs
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 008 Peer Reviewer Dr McBride ID physician, Wisconsin TB affects 1/3rd of the population and one patient dies every 20 seconds from TB. Without treatment 50% of pulmonary TB patients will be dead in 5 years. In low to middle income countries both TB and HIV can be ubiquitous, poor compliance can lead to drug resistance and malnourished infants are highly susceptible. TB can be very complex and this post will hopefully give you the backbone t...
Source: Life in the Fast Lane - Category: Emergency Medicine Authors: Tags: Clinical Cases Tropical Medicine Genexpert meningitis TB TB meningitis Tuberculosis Source Type: blogs
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