Mesothelioma Cells Slowed by Grape-Seed Extracts

Extracts from two Italian grape varieties showed distinct anti-cancer activity in three different mesothelioma cell lines, according to a recent multicenter study in Naples, Italy. The in-vitro findings strongly suggest potential of a novel, nonconventional mesothelioma treatment advancement in the future for this aggressive, difficult-to-treat cancer. Previous laboratory studies have shown a negative impact of grape-seed extracts on breast, colon and skin cancer cells, but this was the first using multiple human mesothelioma cell lines. “Our study on mesothelioma seems very promising, but it is a preliminary analysis,” Stefania Crispi, scientist at the National Research Council of Italy, told The Mesothelioma Center at Asbestos.com. “This could represent the first step to the development of future novel drugs.” Next Test is Animal Models Crispi said the next step would be studying the extracts in-vivo (mouse models). A positive result there likely would lead to a clinical trial involving humans with mesothelioma. The Journal of Functional Foods published the study findings in its October 2019 edition. There has been mounting evidence that grape-derived phytochemicals can inhibit cancerous changes to human cells and exert a cytotoxic effect on tumors. One earlier study reported that cabernet sauvignon seed extract showed cytotoxicity on colon cancer cells and amplified the efficacy of chemotherapy. This latest study described the anti-cancer potential of aglianico (re...
Source: Asbestos and Mesothelioma News - Category: Environmental Health Authors: Source Type: news