PHE (Public Health England) Infectious Diseases Strategy 2020 to 2025: Addressing Urgent Threats in the 21st Century

Source: United Kingdom Department of Health (DH). Published: 9/2019. This 21-page strategy outlines Public Health England's work to combat infectious diseases, and sets out the strategic priorities for the five-year period 2020 to 2025. Topics include being a world leader in tackling antimicrobial resistance (AMR), strengthening global health activities to protect health in the United Kingdom and globally, and addressing globalization and climate change, which have the potential to increase the probability of the introduction of global infections like pandemic influenza, together with the speed and reach of further spread. (PDF)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - Category: International Medicine & Public Health Source Type: news

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In this study, we generated two recombinant RABVs, rERAG333E/NiVG and rERAG333E/NiVF, expressing the NiV Malaysian strain attachment glycoprotein (NiV-G) or fusion glycoprotein (NiV-F) gene based on the rERAG333E vector platform. Both rERAG333E/NiVG and rERAG333E/NiVF displayed growth properties similar to those of rERAG333E and caused marked syncytia formation after co-infection in BSR cell culture. Adult and suckling mice intracerebrally inoculated with the recombinant RABVs showed NiV-G and NiV-F expression did not increase the virulence of rERAG333E. Oral vaccination with rERAG333E/NiVG either singularly or combined wi...
Source: Veterinary Microbiology - Category: Veterinary Research Source Type: research
This study aimed to investigate the association between IL-23R gene polymorphisms and BD susceptibility.Methods: Comprehensive literature search was performed across four online databases - PubMed, Embase, Cochrane Library, and Web of science. The included studies had to be published before May 15, 2019. The Newcastle-Ottawa scale was used to assess the quality of every included study, and pooled odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated using the allele model of inheritance to evaluate the potential associations between IL-23R gene polymorphisms and BD risk.Results: In all, 12 case-control s...
Source: Immunological Investigations - Category: Allergy & Immunology Tags: Immunol Invest Source Type: research
Source: World Health Organization, Regional Office for South-East Asia. Published: 9/2019. This 35-page plan builds on and is aligned with the Global Strategic Plan to Strengthen Public Health Preparedness and Response; the World Health Organization's Global Action Plan on Antimicrobial Resistance; the Research and Development Blueprint for action to prevent epidemics; and the Pandemic Influenza Preparedness Framework. It is also guided by regional approaches, networks, and mechanisms for health emergency preparedness and response, such as the Asia Pacific Strategy for Emerging Diseases, a common strategic framework for t...
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - Category: International Medicine & Public Health Source Type: news
United Kingdom Department of Health. 07/13/2017 This chapter of the Health Profile for England details health protection issues that include the prevention and control of infectious diseases, and environmental threats to the health of the population. It has nine sections: Main messages; Introduction; Climate change and extreme events; Outdoor air pollution; Emerging infectious diseases; Pandemic influenza; Antimicrobial resistance and bloodstream infections; Further information; and References. (Text)
Source: Disaster Lit: Resource Guide for Disaster Medicine and Public Health - Category: International Medicine & Public Health Authors: Source Type: news
Authors: Blakiston M, Heffernan H, Roberts S, Freeman J Abstract Antimicrobial resistance (AMR) in general poses a threat to the sustainability of modern healthcare, but a particularly urgent and serious threat is posed by a specific group of antibiotic-resistant bacteria known as carbapenemase-producing Enterobacteriaceae (CPE). CPE are resistant to nearly all antibiotics and include common pathogens such as Escherichia coli and Klebsiella pneumoniae. In New Zealand, the incidence of CPE has increased from three isolates in 2012 to 45 in 2016. The current epidemiology of CPE in New Zealand has similarities with th...
Source: New Zealand Medical Journal - Category: Journals (General) Tags: N Z Med J Source Type: research
What is 'One Health'?
Source: WHO Feature Stories - Category: Global & Universal Tags: antimicrobial resistance [subject], food safety [subject], food poisoning, immunization [subject], vaccination, influenza [subject], flu, seasonal influenza, pandemic influenza, zoonose [subject], animal diseases, FAQ [doctype] Source Type: news
Editor’s Note: This post reflects on a speech on pandemic preparedness Dr. Fauci gave on January 10, 2017 in Washington, DC, hosted by  The Center for Global Health Science and Security at Georgetown University Medical Center, the Harvard Global Health Institute, and Health Affairs. One of the most important challenges facing the new Administration is preparedness for the pandemic outbreak of an infectious disease. Infectious diseases will continue to pose a significant threat to public health and the economies of countries worldwide. The U.S. government will need to continue its investment to combat these ...
Source: Health Affairs Blog - Category: Health Management Authors: Tags: Featured Global Health Policy Ebola HIV/AIDS NIH pandemic preparedness Zika Source Type: blogs
As almost everyone in the business of caring for the health of humans and animals is acutely aware, on our current trajectory, it is estimated that antimicrobial resistance (AMR) will cause 10 million deaths annually by 2050, with many arising from simple infections following routine operations. This is why the UK government has placed antimicrobial resistance at the top of its risk register alongside terrorism and pandemic influenza.
Source: The Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research
We describe antibiotic usage patterns and assess factors contributing to antibiotic usage among adults presenting with acute febrile illness (AFI) in primary care settings in Singapore.MethodsWe analyzed data from the Early Dengue infection and outcome study. Adults with AFI presenting at 5 Singapore polyclinics were included. We used multivariable logistic regression to assess demographic, clinical and laboratory factors associated with antibiotic usage among adults with AFI.ResultsBetween December 2007 and February 2013, 1884 adult AFI patients were enrolled. Overall, 16% of adult AFI patients reported antibiotic use. We...
Source: Antimicrobial Resistance and Infection Control - Category: Infectious Diseases Source Type: research
Dr Keiji Fukuda is Special Representative for Antimicrobial Resistance in the office of the WHO Director-General. From September 2010 until November 2015, Keiji Fukuda served as the Assistant Director-General for Health Security.
Source: WHO Avian Influenza - Category: Infectious Diseases Tags: avian influenza [subject], bird flu, avian flu, fowl plague, influenza in birds, avian bird flu, h5n1, epidemiology [subject], surveillance, influenza [subject], flu, seasonal influenza, pandemic influenza, influenza [subject], flu, seasonal influenza, pa Source Type: news
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