Ketamine and peripheral inflammation.
In conclusion, ketamine appears as a unique "homeostatic regulator" of the acute inflammatory reaction and the stress-induced immune disturbances. This is of some interest at a moment when the short- and long-term deleterious consequences of inadequate inflammatory reactions are increasingly reported. Large-scale studies showing improved patient's outcome are, however, required before to definitively assert the clinical reality of this positive effect.
PMID: 23574634 [PubMed - in process]
Source: CNS Neuroscience and Therapeutics - Category: Neuroscience Authors: De Kock M, Loix S, Lavand'homme P Tags: CNS Neurosci Ther Source Type: research