Pharmacokinetics of quinine in healthy Nigerian subjects and in patients with uncomplicated malaria: analysis of data using a population approach

ConclusionsThe study findings suggest that clinical interventions aimed at enhancing the safety and tolerance of quinine might be achieved by a rational decrease in dose size and/or dosing interval, post-48 h of chronic quinine administration, in malaria-infected subjects.
Source: Current Therapeutic Research - Category: Drugs & Pharmacology Source Type: research