Role of differential proteomics in studying pharmacological mechanisms of traditional Chinese medicines.

Role of differential proteomics in studying pharmacological mechanisms of traditional Chinese medicines. J Pharm Pharm Sci. 2019;22(1):424-439 Authors: Wang Y, Javed I, Zhang X, Liu D, Zhang C Abstract Traditional Chinese Medicines (TCMs) have been used for more than 3,000 years. However, most TCMs are used based on previous experience, and their exact mechanisms are still unclear. Proteomics, as a major component of systems biology, is an appropriate tool that could bring breakthroughs in the study of pharmacological mechanisms of TCMs. Researchers made substantial progress by using the proteomics approach to investigate the mechanism of TCMs. In this review, we summarize the current applications of proteomics in the mechanistic study of TCMs. Proteomics technologies and strategies that might be used in the future to enhance the study of TCMs are also discussed. PMID: 31509503 [PubMed - in process]
Source: Journal of Pharmacy and Pharmaceutical Sciences - Category: Drugs & Pharmacology Tags: J Pharm Pharm Sci Source Type: research