PSGL1 ‐deficient mice develop spontaneous pulmonary hypertension associated to systemic sclerosis

ConclusionPSGL ‐1 absence induces reduction of Treg, NO production and ERα expression and the increase of Angiotensin II in the lungs of female mice, favoring the development of PAH

Source: Arthritis and Rheumatology - September 10, 2019 Category: Rheumatology Authors: Rafael Gonz ález‐Tajuelo, María de la Fuente‐Fernández, Daniel Morales‐Cano, Antonio Muñoz‐Callejas, Elena González‐Sánchez, Javier Silván, Juan Manuel Serrador, Susana Cadenas, Bianca Barreira, Marina Espartero‐Santos, Carlos Tags: FULL LENGTH Source Type: research