Presumed antiphospholipid syndrome and thrombotic thrombocytopenic purpura: An infrequent association

Antiphospholipid syndrome (APS) is an autoimmune disease that demonstrates antiphospholipid antibodies that cause hypercoagulability and leads to venous and arterial thrombosis. Autoantibodies to a disintegrin ‐like and metalloprotease with thrombospondin type I motif, member 13 (ADAMTS 13) play a role in the microthrombosis of thrombotic thrombocytopenic purpura in APS patients. AbstractAntiphospholipid syndrome (APS) is an autoimmune disease that demonstrates antiphospholipid antibodies that cause hypercoagulability and leads to venous and arterial thrombosis. Autoantibodies to a disintegrin ‐like and metalloprotease with thrombospondin type I motif, member 13 (ADAMTS 13) play a role in the microthrombosis of thrombotic thrombocytopenic purpura in APS patients.

Source: Clinical Case Reports - September 8, 2019 Category: General Medicine Authors: Hallie Hanna Dolin, Mark Dziuba, Scott M. Pappada, Thomas John Papadimos Tags: CASE REPORT Source Type: research