Amelioration of estrogen-induced endometrial hyperplasia in female rats by hemin via heme-oxygenase-1 expression, suppression of iNOS, p38MAPK and Ki67.

In conclusion, upregulation of HO-1 expression via hemin has ameliorative effect against EH through its anti-oxidant, anti-inflammatory and anti-proliferative actions. PMID: 31505119 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31505119?dopt=Abstract

Source: Canadian Journal of Physiology and Pharmacology - September 9, 2019 Category: Drugs & Pharmacology Authors: Ali FF, Abdelzaher W, Ibrahim RA, Elroby Ali D Tags: Can J Physiol Pharmacol Source Type: research