Bidentate ligands and their Cu(II) complexes: Structural characterization, electrochemical properties and biological evaluation

Publication date: Available online 11 September 2019Source: Journal of Molecular StructureAuthor(s): Ferhan Tümer, Seyit Ali Güngör, Muhammet Köse, Feridun Koçer, Mehmet TümerAbstractIn this manuscript, three bidentate ligands 2-[(2-methoxybenzylidene)amino]phenol (HA1), 2-[(3,4,5-trimethoxybenzylidene) amino]phenol (HA2) and 2-[(2,3,4-trimethoxybenzylidene) amino]phenol (HA3) were synthesized from the reaction of the 2-aminophenol and methoxy benzaldehyde derivatives in MeOH solution. The Cu2+ metal complexes of these ligands were obtained in the 1:1 (M:L) ratio. All the compounds were characterized by the micro analytical and spectroscopic techniques. The single crystals of the bidentate ligands (HA2 and HA3) were obtained from the recrystallization from the MeOH solution and their structural characterizations were conducted by the X-ray diffraction method. Antimicrobial activity studies of the bidentate ligands and their Cu2+ metal complexes were tested towards S. aureus, E. coli, B. cereus, B. subtilis, S. typhimurium as bacteria and C. albicans as fungi and the complex Cu2+ of the ligand HA2 showed the highest activity against to the S. aureus. While the ligands HA2 and HA3 do not show the activity against the bacteria and fungi, the ligand HA1 has the activity against to the S. typhimurium, S. aureus and C. albicans. Electrochemical behaviours of all compounds have been investigated in DMF solution and it was found that the cathodic and anodic values of the [CuA3(...
Source: Journal of Molecular Structure - Category: Molecular Biology Source Type: research