Multiple sevoflurane exposures during pregnancy inhibit neuronal migration by upregulating prostaglandin D2 synthase.

CONCLUSION: Our study suggests that multiple sevoflurane exposures in pregnant mice may induce neuronal migration deficits in offspring mice. Additional studies comprising long-term behavioral tests are required to confirm the effects of sevoflurane exposure during pregnancy.
PMID: 31499143 [PubMed - as supplied by publisher]

Source: International Journal of Developmental Neuroscience - September 5, 2019 Category: Neuroscience Authors: Chai D, Cheng Y, Sun Y, Yan J, Hu R, Zhang L, Jiang H Tags: Int J Dev Neurosci Source Type: research