Toxic shock syndrome toxin 1-producing methicillin-resistant Staphylococcus aureus of clonal complex 5, the New York/Japan epidemic clone, causing a high early mortality rate in patients with bloodstream infections.

Conclusions: Both host-related factors, increased Pitt bacteremia score and advanced age, as well as a pathogen-related factor, carriage of tst-1 by causative MRSA isolates, were risk factors for two-week mortality in patients with BSIs, and careful management of patients with BSIs caused by the New York/Japan epidemic clone is needed to improve clinical outcomes.
PMID: 31501145 [PubMed - as supplied by publisher]

Source: Antimicrobial Agents and Chemotherapy - September 8, 2019 Category: Microbiology Authors: Kim D, Hong JS, Yoon EJ, Lee H, Kim YA, Shin KS, Shin JH, Uh Y, Shin JH, Park YS, Jeong SH Tags: Antimicrob Agents Chemother Source Type: research