Development and Validation of Quantitative Real-Time PCR for the Detection of Residual CHO Host Cell DNA and Optimization of Sample Pretreatment Method in Biopharmaceutical Products.

Conclusions: These results all indicated that the method for determination of residual DNA in biological products expressed from CHO cells is sensitive, accurate and robust.
PMID: 31496923 [PubMed]

Source: Biological Procedures Online - September 11, 2019 Category: Molecular Biology Authors: Zheng W, Jiang L, Lei Q, Yang J, Gao X, Wang W, Zhang Y, Kong T, Chen Q, Li G Tags: Biol Proced Online Source Type: research