Pulse generator battery life in deep brain stimulation: out with the old … in with the less durable?
ConclusionsNewer devices are more versatile than the older generation. Their battery life is however significantly shorter. Development of next-generation devices needs to address this issue in order to limit health risks and reduce financial costs.
CONCLUSIONS: QSM-based images allow for confident localization of borders of the GPi that is superior to T1w and T2w images. High-contrast hybrid images can be used for precisely directed DBS targeting, e.g., GPi DBS for the treatment of advanced Parkinson's disease. PMID: 31604332 [PubMed - as supplied by publisher]
CONCLUSIONS: Intraoperative MRI-guided lead placement in patients with dystonia showed improvement in clinical outcomes comparable to previously reported results using awake MER-guided lead placement. The accuracy of lead placement was high, and the procedure was well tolerated in the majority of patients. However, a number of patients experienced serious adverse events that were attributable to the introduction of a novel technique into a busy neurosurgical practice, and which led to the revision of protocols, product inserts, and on-site training. PMID: 31604331 [PubMed - as supplied by publisher]
Abstract Over the last two decades, deep brain stimulation (DBS) has gained popularity as a treatment of severe and medically refractory obsessive-compulsive disorder (OCD), often using brain targets informed by historical lesional neurosurgical procedures. Paradoxically, the use of DBS in OCD has led some multidisciplinary teams to revisit the use of lesional procedures, especially anterior capsulotomy (AC), although significant aversion still exists toward the use of lesional neurosurgery for psychiatric disorders. This paper aims to review all literature on the use of AC for OCD to examine its effectiveness and...
Deep brain stimulation (DBS) typically has been delayed until late stage of Parkinson's disease (PD), a mean of 14 –15 years after diagnosis. EARLYSTIM study applied DBS in patients with PD presenting motor complications for less than three years, and showed that early stimulation offered greater benefit than best medical therapy in all primary and major secondary end points. Based on the results of EARLYSTIM study, the U.S. Food and Drug Administration recently approved DBS for use in people with PD of at least four years duration and with recent onset of motor complications.
Deep brain stimulation (DBS) of a region called the subcallosal cingulate appears to be safe and effective at reducing symptoms of depression in patients with treatment-resistant depression over time, according to asmall study inAJP in Advance.Previous studies suggest that up to one-third of all patients with major depression have treatment-resistant depression (that is, they fail to experience symptom improvements during two or more antidepressant trials). “Given that patients with treatment-resistant depression are highly susceptible to recurrent depressive episodes, the ability of DBS or any treatment to support l...
Title: Deep Brain Stimulation May Relieve Ringing in the Ears: StudyCategory: Health NewsCreated: 10/7/2019 12:00:00 AMLast Editorial Review: 10/8/2019 12:00:00 AM
The effects of the therapy in a small group of patients were long-lasting, researchers say, adding to evidence that the approach works for treatment-resistant depression.
MONDAY, Oct. 7, 2019 -- Ringing in the ears (tinnitus) can make life miserable, but a brain implant may help, preliminary research suggests. In a phase 1 trial of five patients whose severe tinnitus did not respond to other treatments, deep brain...
A study that gathered data for at least 8 years has shown that deep brain stimulation can have a robust, sustained effect in people with severe depression.
High cognitive reserve is associated with milder cognitive and motor deficits in Parkinson's disease (PD). We investigated whether educational status (as a proxy for cognitive reserve) could modulate dual-task (DT) related gait changes after subthalamic nucleus deep brain stimulation (STN-DBS) in PD.