A comparative cost-utility analysis of postoperative calcium supplementation strategies used in the current management of hypocalcemia

Symptomatic hypocalcemia is a common complication of total thyroidectomy. Management strategies include responsive treatment initiation for symptoms or prevention by routine or parathyroid hormone-directed calcium supplementation. The comparative cost-effectiveness of even the most often utilized strategies is unclear.
Source: Surgery - Category: Surgery Authors: Source Type: research

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This study was analyzed using the Surveillance, Epidemiology, and End Results (SEER) database. Joinpoint regression models, linear regression models, Kaplan-Meier survival curves and Cox regression models were used to study the trends in incidence, survival rate and median survival time and to detect the risk factors affecting prognosis in patients with anaplastic thyroid cancer. RESULTS: While the incidence rate and truncated incidence rate fluctuated slightly over the past 30 years, they were relatively stable and had no obvious upward trend (APC = -0.22 and 0.24, respectively, P>0.05). The median survival was 3.1...
Source: American Journal of Translational Research - Category: Research Tags: Am J Transl Res Source Type: research
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Source: Endocrine - Category: Endocrinology Source Type: research
Conclusion: Our findings, along with other reports, suggest that MKIs is an effective neoadjuvant therapy and should be considered as a therapeutic strategy for unresectable grossly locally invasive thyroid carcinomas.
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
This population-based cohort study uses the Health Insurance Review and Assessment database of South Korea to examine the association between adverse pregnancy outcomes and radioactive iodine treatment after thyroidectomy among South Korean women of childbearing age with thyroid cancer.
Source: JAMA Internal Medicine - Category: Internal Medicine Source Type: research
Authors: Karakış A, Tapar H, Özsoy Z, Suren M, Dogru S, Karaman T, Karaman S, Sahin A, Kanadlı H Abstract INTRODUCTION: Bilateral Superficial Cervical Plexus Block (BSCPB) is a common method used for analgesia in thyroid surgery. We investigated the analgesic efficacy of bilateral superficial cervical plexus block in the intraoperative and postoperative periods. MATERIALS AND METHODS: Patients (n = 46) undergoing thyroidectomy were randomly separated into the following 2 groups: the General Anesthesia Group (GA; n = 23) and the general anesthesia plus BSCPB Group (GS; n = 23). The in...
Source: Revista Brasileira de Anestesiologia - Category: Anesthesiology Tags: Rev Bras Anestesiol Source Type: research
CONCLUSIONS: A novel combined sonographic and elastosonographic parameter evaluation improved diagnostic accuracy for identifying thyroid nodules suspicious of malignancy. PMID: 31625708 [PubMed - as supplied by publisher]
Source: Minerva Endocrinologica - Category: Endocrinology Tags: Minerva Endocrinol Source Type: research
ConclusionOverall, the GBI scores are positive, thereby showing an improvement in quality of life since having total thyroidectomy for Graves. Pre-operative communication was of paramount importance. It should be made clear to patients that they will require medication after surgery. The majority of patients stated they would prefer to know about “minor” post -operative side effects like weight gain or mood change post op. This highlights the importance of the consenting process- Montgomery Ruling-that clinicians explain the risks involved with surgery according to what the patient would deem a risk. In additio...
Source: The Surgeon - Category: Surgery Source Type: research
Conclusion: NTT for GD is not superior to TT regarding transient postoperative hypoparathyroidism.
Source: Annals of Surgery - Category: Surgery Tags: ESA-RANDOMIZED CONTROLLED TRIALS Source Type: research
ConclusionLevothyroxine-induced liver injury is a rare, and in the present case report, a self-limiting, adverse effect. The diagnosis of our patient was confirmed via noninvasive diagnostic methods. Knowledge of this rare adverse effect is important in the differential diagnosis of patients who have commenced on levothyroxine and have deranged liver enzymes in the context of hypothyroidism.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research
Thyroidectomy is a definitive treatment for hyperthyroidism. The purpose of this study is to examine how often patients with hyperthyroidism are referred for thyroidectomy and what are the common reasons for referral.
Source: Journal of Surgical Research - Category: Surgery Authors: Source Type: research
More News: Calcium | Hormones | Surgery | Thyroidectomy