Danish experience of meticillin-resistant Staphylococcus aureus eradication with emphasis on nose-throat colonization and supplementary systemic antibiotic treatment

Publication date: Available online 9 September 2019Source: Journal of Hospital InfectionAuthor(s): Ina Sleimann Petersen, Judit Marta Christensen, Anne Bak Zeuthen, Pia Bruun MadsenSummaryThe study-aim was to evaluate the Danish national Board of Health's guidance for treating MRSA carriage focusing on MRSA nose-throat carriage and use of supplementary systemic antibiotics. We analyze results of MRSA eradication treatment of 358 patients, focusing on those with nose (n=58) or throat (n=183) MRSA colonization. We found that the Danish guidance for treating MRSA have greater success for patients with nose colonization (66%) compared to throat colonization (41%), even though the cumulative eradication rates were equal after additional three treatment cycles (71% versus 73%). We find no positive effect of supplementing the colonization treatment with systemic antibiotics.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research