Association of fragmented QRS with left atrial scarring in patients with persistent atrial fibrillation undergoing radiofrequency catheter ablation

Fragmented QRS (fQRS) in 12-lead ECG is a non-invasive marker of intra-myocardial conduction delay due to ventricular scarring which has not been studied in AF before.
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research

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ConclusionA considerable burden of previously unknown AF was detected when long-term monitoring was applied in at-risk patients. Biomarkers were associated with AF incidence and improved prediction of long AF episodes.
Source: American Heart Journal - Category: Cardiology Source Type: research
ConclusionsOur results suggest that sex-specific differences in LV geometry, hyper-contractility and diastolic function, not greater degree of LV myopathy, contribute to a higher, age-independent risk of diastolic HF in women with HCM.Graphical abstract
Source: American Heart Journal - Category: Cardiology Source Type: research
Conditions:   Auricular Fibrillation;   Anticoagulant Drugs Intervention:   Sponsors:   Hospital Italiano de Buenos Aires;   Boehringer Ingelheim Active, not recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Paroxysmal Atrial Fibrillation Intervention:   Device: POLARx™ Cardiac Cryoablation System Sponsor:   Boston Scientific Corporation Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
MONDAY, Oct. 21, 2019 -- American Indians have a higher risk for incident atrial fibrillation (AF) compared with all other racial and ethnic groups, according to a study published online Oct. 21 in Circulation. Jos é M. Sanchez, M.D., from the...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
This patient who presented with acute heart failure has a history of heart failure and atrial fibrillation:This was interpreted as " lateral ischemia " .The patient's previous hospital admission had been predicated on this " ischemia. "What do you think?There is atrial fibrillation with a controlled ventricular rate.  There is scooped ST depression in II, III, aVF and especially in V5, V6.There are 4 categories of etiologies of ST depression in the context of a normal QRS:1. Ischemia2. Hypokalemia3. Digoxin4. Baseline/non-pathologic--When the QT interval is very short, think digoxin.--When the pati...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
Publication date: Available online 19 October 2019Source: Life SciencesAuthor(s): Lu Fu, Fang Rao, Feihong Lian, Hui Yang, Sujuan Kuang, Shulin Wu, Chunyu Deng, Yumei XueAbstractAimsTo explore the atrial electrical remodeling and the susceptibility of atrial fibrillation (AF) in diabetic rats.Materials and methodsZucker diabetic fatty (ZDF) rats were chosen as diabetic animal model, and age-matched non-diabetic littermate Zucker lean (ZL) rats as control. AF susceptibility was determined by electrophysiological examination. The current density of Ito, IKur and ICa-L were detected by whole-cell patch-clamp technique, and io...
Source: Life Sciences - Category: Biology Source Type: research
This study assessed patient preference for warfarin or DOAC based on a willingness to pay more for potential DOAC benefits. Current warfarin patients with atrial fibrillation or venous thromboembolism enrolled in the University of Utah Health Thrombosis Service were given a one-time electronic survey that assessed preferences between warfarin and DOACs using scenarios comparing effectiveness, safety, and convenience. When DOACs were preferred, patients were asked how much more they would be willing to pay monthly for the perceived advantages associated with DOACs. With 123 completed surveys, 68% of patients preferred to st...
Source: Journal of Thrombosis and Thrombolysis - Category: Hematology Source Type: research
AbstractVery limited but promising experiences with the use of direct factor Xa inhibitors for the treatment of heparin-induced thrombocytopenia (HIT) have been reported. This contribution features our first experience with the use of apixaban (without a pre-treatment with parenteral anticoagulant) to treat a case of HIT which developed in a patient after multiple heart replacement surgery. Apixaban was effective, well tolerated and safe. An apixaban-calibrated chromogenic anti-Xa activity assessment was used to monitor apixaban activity throughout the therapy. Patient continued on apixaban for the prevention of thrombosis...
Source: Journal of Thrombosis and Thrombolysis - Category: Hematology Source Type: research
Atrial fibrillation (AF), a risk factor for strokes and systemic thromboembolisms, is associated with unfavorable fibrin clot properties and increased thrombus formation in peripheral blood. The left atrial appendage (LAA) is known to be the primary site of thrombus formation.
Source: International Journal of Cardiology - Category: Cardiology Authors: Source Type: research
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