Increased adenosine-to-inosine RNA editing in rheumatoid arthritis.

CONCLUSION: A previously unrecognized regulation and role of ADAR1p150-mediated A-to-I RNA editing in post-transcriptional control in RA underpins therapeutic response and fuels inflammatory gene expression, thus representing an interesting therapeutic target. PMID: 31493964 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31493964?dopt=Abstract

Source: Journal of Autoimmunity - September 3, 2019 Category: Allergy & Immunology Authors: Vlachogiannis NI, Gatsiou A, Silvestris DA, Stamatelopoulos K, Tektonidou MG, Gallo A, Sfikakis PP, Stellos K Tags: J Autoimmun Source Type: research