Investigation of the relationship between IL-6 and type 2 biomarkers in severe asthma

Combination of IL-6 (non-Type 2 asthma) and FeNO or blood eosinophil count (Type 2 asthma) identified asthma endotypes related to asthma severity, exacerbations, and responsiveness to corticosteroids and potential for response to anti-Type 2 and anti-IL-6 treatment.

Source: Journal of Allergy and Clinical Immunology - September 8, 2019 Category: Allergy & Immunology Authors: Xingnan Li, Annette T. Hastie, Michael C. Peters, Gregory A. Hawkins, Wanda Phipatanakul, Huashi Li, Wendy C. Moore, William W. Busse, Mario Castro, Serpil C. Erzurum, Benjamin Gaston, Elliot Israel, Nizar N. Jarjour, Bruce D. Levy, Sally E. Wenzel, Debor Source Type: research