Preclinical evaluation of an mRNA HIV vaccine combining rationally selected antigenic sequences and adjuvant signals (HTI-TriMix): Erratum Phase I clinical trial of an intranodally administered mRNA-based therapeutic vaccine against HIV-1 infection: Erratum

No abstract available
Source: AIDS - Category: Infectious Diseases Tags: Errata Source Type: research

Related Links:

A 25 year-old tuberculosis patient is treated at her home in Funafuti, the main island of Tuvalu in the South Pacific. Credit: UNDP Tuvalu/Aurélia Rusek.By External SourceUNITED NATIONS, Oct 17 2019 (IPS) A staggering 1.5 million people died from tuberculosis (TB) last year, the UN health agency said on Thursday, in an appeal for far greater funding and political support to eradicate the curable and preventable disease. Caused by the bacteria Mycobacterium tuberculosis, TB commonly causes persistent coughing, fatigue and weight loss. According to the World Health Organization (WHO) and its latest Global TB Report, a...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Global Headlines Health Poverty & SDGs Source Type: news
Publication date: December 2019Source: Microbial Pathogenesis, Volume 137Author(s): Faruq Abdulla, Utpal Kumar Adhikari, M. Kamal UddinAbstractTill now, AIDS, caused by the human immunodeficiency virus (HIV) is still a severe health problem worldwide. It weakens the immune system by targeting the T-helper cells. Specifically, the severity of the pandemic HIV-1 makes the emergence of an enduring effective vaccine against HIV-1. Therefore, we have applied a series of immunoinformatics approaches to the four conserved domains of HIV-1 integrase (IN) proteins to design an effective multi-epitope based subunit vaccine which mig...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Condition:   HIV-1-infection Interventions:   Biological: Vaccine and vedolizumab (Entyvio);   Biological: Placebo vaccine and vedolizumab infusion (Entyvio);   Biological: Placebo vaccine and placebo infusion Sponsors:   French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS);   EuroVacc Foundation;   European AIDS Treatment Group (EATG);   Medical Research Council;   University College London, UK.;  ...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   HIV-1-infection Interventions:   Biological: Vaccine and vedolizumab (Entyvio);   Biological: Placebo vaccine and vedolizumab infusion (Entyvio);   Biological: Placebo vaccine and placebo infusion Sponsors:   French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS);   EuroVacc Foundation;   European AIDS Treatment Group (EATG);   Medical Research Council;   University College London, UK.;  ...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   HIV-1-infection Interventions:   Biological: Vaccine and vedolizumab (Entyvio);   Biological: Placebo vaccine and vedolizumab infusion (Entyvio);   Biological: Placebo vaccine and placebo infusion Sponsors:   French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS);   EuroVacc Foundation;   European AIDS Treatment Group (EATG);   Medical Research Council;   University College London, UK.;  ...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   HIV-1-infection Interventions:   Biological: Vaccine and vedolizumab (Entyvio);   Biological: Placebo vaccine and vedolizumab infusion (Entyvio);   Biological: Placebo vaccine and placebo infusion Sponsors:   French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS);   EuroVacc Foundation;   European AIDS Treatment Group (EATG);   Medical Research Council;   University College London, UK.;  ...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   HIV-1-infection Interventions:   Biological: Vaccine and vedolizumab (Entyvio);   Biological: Placebo vaccine and vedolizumab infusion (Entyvio);   Biological: Placebo vaccine and placebo infusion Sponsors:   French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS);   EuroVacc Foundation;   European AIDS Treatment Group (EATG);   Medical Research Council;   University College London, UK.;  ...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Background: Very limited data are available on the immunovirological outcomes after 13-valent pneumococcal conjugate vaccine (PCV13) in antiretroviral therapy (ART)-treated patients. The aim of this study was to assess the immune-virological outcomes in HIV-1-infected ART-treated patients on stable virological suppression who underwent pneumococcal conjugate vaccination. Methods: Retrospective, cohort study on ART-treated HIV-1-infected individuals, age at least 18 years, with three consecutive determinations of HIV-RNA less than 50 copies/ml before the administration of PCV13 (baseline) at San Raffaele Hospital and w...
Source: AIDS - Category: Infectious Diseases Tags: CLINICAL SCIENCE Source Type: research
Conclusion: Volunteers showed a sustained high commitment. No long-term safety alert was identified during the postvaccine follow-up. Participating in vaccine trials did not increase risky behaviors for HIV infection. Vaccine-induced seropositivity may persist for more than 23 years after receiving rgp160.
Source: AIDS - Category: Infectious Diseases Tags: EPIDEMIOLOGY AND SOCIAL Source Type: research
Vaccine knowledge and anticipated rates of vaccination even lower for pneumococcal disease
Source: The Doctors Lounge - Oncology - Category: Cancer & Oncology Tags: Cardiology, Endocrinology, Family Medicine, Geriatrics, Gynecology, Infections, AIDS, Internal Medicine, Allergy, Critical Care, Emergency Medicine, Nursing, Oncology, Pathology, Pediatrics, Pharmacy, Pulmonology, Rheumatology, Institutional, Source Type: news
More News: AIDS Vaccine | Clinical Trials | HIV AIDS | Infectious Diseases | Vaccines