ASNC releases directive on cardiac amyloidosis imaging
The American Society of Nuclear Cardiology (ASNC) has published a set of recommendations...Read more on AuntMinnie.comRelated Reading: Imaging groups oppose cuts in myocardial PET rates ASNC names Beanlands as president ASNC releases new guidelines for SPECT MPI SNMMI, ASNC offer guidelines for myocardial perfusion imaging with PET ASNC, SNMMI advise on cardiac sarcoidosis
Authors: Elwazir MY, Bois JP, Abouezzeddine OF, Chareonthaitawee P Abstract Infiltrative heart disease is an encompassing term referring to different pathological entities that involve infiltration of the myocardium by either abnormal substances or inflammatory cells. These infiltrates can impair cellular function, induce necrosis and fibrosis, or otherwise disrupt myocardial architecture resulting in a wide spectrum of structural and functional impairment. Depending on the specific disorder and stage of disease, patients may present with minimal cardiac abnormalities, or may have findings of advanced restrictive a...
Preema Sinha, Saikat Bhattacharjee, Deep Kumar Raman, Aradhana SoodIndian Journal of Dermatology 2020 65(1):50-52 Cutaneous lesions in sarcoidosis are seen in nearly 20–30% and include lesions like papules, nodules, plaques, infiltrated scars, and erythema nodosum. Lichenoid variants of cutaneous sarcoidosis, a type of papular variant is quite rare. Herein we report a case of lichenoid sarcoidosis in a 40-year-old male who presented with raised itchy lesions over his legs and lower back of 8 years duration.
Arrhythmogenic cardiomyopathy (ACM) is an arrhythmogenic disorder of the myocardium not secondary to ischemic, hypertensive, or valvular heart disease. ACM incorporates a broad spectrum of genetic, systemic, infectious, and inflammatory disorders. This designation includes, but is not limited to, arrhythmogenic right/left ventricular cardiomyopathy, cardiac amyloidosis, sarcoidosis, Chagas disease, and left ventricular noncompaction. The ACM phenotype overlaps with other cardiomyopathies, particularly dilated cardiomyopathy with arrhythmia presentation that may be associated with ventricular dilatation and/or impaired systolic function.
Cardiac positron emission tomography (PET) is routinely utilized to diagnose cardiac sarcoidosis, but may be positive in other cardiac conditions that result in myocardial inflammation. ATTR cardiac amyloidosis, an infiltrative disease that causes atrial arrhythmias and heart failure, is not typically thought to present with an inflammatory process. However, we observed four cases in which 18F-flurodeoxyglycose (FDG) PET scan findings were suspicious for cardiac sarcoidosis, but right ventricular endomyocardial biopsy (RV EMB) pathology specimens revealed ATTR wild-type (ATTRwt) cardiac amyloidosis.
Authors: Boutagy NE, Feher A, Alkhalil I, Umoh N, Sinusas AJ Abstract Multimodality cardiovascular imaging is routinely used to assess cardiac function, structure, and physiological parameters to facilitate the diagnosis, characterization, and phenotyping of numerous cardiovascular diseases (CVD), as well as allows for risk stratification and guidance in medical therapy decision-making. Although useful, these imaging strategies are unable to assess the underlying cellular and molecular processes that modulate pathophysiological changes. Over the last decade, there have been great advancements in imaging instrumenta...
Conditions: Cardiac Failure; Coronary Artery Disease; Sarcoidosis; Amyloidosis; Lupus; Myocarditis; Drug Toxicity Intervention: Procedure: Diagnostic Test: Myostrain Sponsor: University of Kansas Medical Center Not yet recruiting
Conclusion: These low voltages are like those found in patients with carcinoid syndrome, severe cardiac adiposity, cardiac amyloidosis, and cardiac sarcoidosis.Cardiology 2018;141:172 –175
Abstract Nuclear cardiology is one of the major fields of nuclear medicine practice. Myocardial perfusion studies using single-photon emission computed tomography (SPECT) have played a crucial role in the management of coronary artery diseases. Positron emission tomography (PET) has also been considered an important tool for the assessment of myocardial viability and perfusion. However, the recent development of computed tomography (CT)/magnetic resonance imaging (MRI) technologies and growing concerns about the radiation exposure of patients remain serious challenges for nuclear cardiology. In response to these c...