Toxoplasma gondii ROP16 kinase silences the cyclin B1 gene promoter by hijacking host cell UHRF1-dependent epigenetic pathways.

This study demonstrates that Toxoplasma hijacks a new epigenetic initiator, UHRF1, through an early event initiated by the ROP16 parasite kinase.
PMID: 31492965 [PubMed - as supplied by publisher]

Source: Cellular and Molecular Life Sciences : CMLS - September 5, 2019 Category: Cytology Authors: Sabou M, Doderer-Lang C, Leyer C, Konjic A, Kubina S, Lennon S, Rohr O, Viville S, Cianférani S, Candolfi E, Pfaff AW, Brunet J Tags: Cell Mol Life Sci Source Type: research