Benzodiazepines Suppress Neuromodulatory Effects of Pudendal Nerve Stimulation on Rat Bladder Nociception.

CONCLUSIONS: This study suggests that inhibitory effects of bPNS on bladder pain could be suppressed in subjects receiving benzodiazepine therapy, suggesting that potential clinical testing of pudendal nerve stimulation for the treatment of painful bladder syndromes may be confounded by the use of benzodiazepines. Clinical assessment of other forms of neuromodulation should also be screened for impacts of benzodiazepines. PMID: 31490256 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31490256?dopt=Abstract

Source: Anesthesia and Analgesia - September 2, 2019 Category: Anesthesiology Authors: Ness TJ, McNaught J, Clodfelder-Miller B, Nelson DE, Su X Tags: Anesth Analg Source Type: research