Changing the Rules of the Game: How Winners Become Losers during Oncogenic Cell Selection.

Changing the Rules of the Game: How Winners Become Losers during Oncogenic Cell Selection.
Cell Stem Cell. 2019 Sep 05;25(3):299-300
Authors: Villa Del Campo C, Torres M
Abstract
As we age, our tissues become a mosaic of random mutations, many of which are oncogenic and promote the expansion of their carrier cells. In this issue of Cell Stem Cell, Fernandez-Antoran et al. (2019) show how commonly used medical procedures modify cell selection dynamics to either expand or eliminate cells carrying oncogenic p53 mutations.
PMID: 31491391 [PubMed - in process]

Source: Cell Stem Cell - September 4, 2019 Category: Stem Cells Authors: Villa Del Campo C, Torres M Tags: Cell Stem Cell Source Type: research