Microcatheter delivery of neurotherapeutics: compatibility with mesenchymal stem cells.

CONCLUSIONS: BM-hMSC-Delta-24 is compatible with a wide variety of microcatheters and medications commonly used in neuroendovascular therapy. Stem cell viability and viral agent activity do not appear to be affected by catheter configuration or injection velocity. Commercially available microcatheters can be used to deliver stem cell neurotherapeutics via intraarterial routes.
PMID: 31491769 [PubMed - as supplied by publisher]

Source: Journal of Neurosurgery - September 5, 2019 Category: Neurosurgery Authors: Srinivasan VM, Gumin J, Camstra KM, Chen SR, Johnson JN, Shimizu Y, Parker Kerrigan BC, Shpall EJ, Lang FF, Kan P Tags: J Neurosurg Source Type: research