Chronic wounds: the challenges of appropriate management.

This article discusses chronic wound management based on the TIME framework, examining the aspects to be considered when managing chronic wounds. It also describes the process of dressing selection for overcoming the various barriers to wound healing, specifically discussing the AQUACEL family of dressings. PMID: 31479336 [PubMed - in process]
Source: British Journal of Community Nursing - Category: Nursing Authors: Tags: Br J Community Nurs Source Type: research

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Wound healing-promoting peptides exhibit excellent therapeutic potential in regenerative medicine. However, amphibian-derived wound healing-promoting peptides and their mechanism of action remain to be further elucidated. We hereby characterized a wound healing-promoting peptide, Ot-WHP, derived from Chinese concave-eared frog Odorrana tormota. It efficiently promoted wound healing in a mouse model of full-thickness wounds. Ot-WHP significantly increased the number of neutrophils in wounds, and modestly promoted neutrophil phagocytosis and phorbol myristate acetate (PMA)-induced neutrophil extracellular trap formation. Ot-...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Publication date: Available online 9 October 2019Source: Reactive and Functional PolymersAuthor(s): Liora Colobatiu, Alexandru Gavan, Adrian-Valentin Potarniche, Vasile Rus, Zorita Diaconeasa, Andrei Mocan, Ioan Tomuta, Simona Mirel, Marian MihaiuAbstractDelayed wound healing is a major complication of diabetes and the medical treatment of such wounds still remains a challenge. Among the modern wound dressings, film dressings are considered to be one of the major advances in wound management. In the current study, the feasibility of using a previously developed and optimized bioactive compounds-loaded chitosan film formula...
Source: Reactive and Functional Polymers - Category: Chemistry Source Type: research
Soft Matter, 2019, Accepted Manuscript DOI: 10.1039/C9SM01296F, PaperZiran Zhai, Keming Xu, Leixia Mei, Can Wu, Jing Liu, Ziqi Liu, Lanxin Wan, Wenying Zhong Injectable hydrogels are promising materials for applications in non-compressive wound management. Yet difficulties remain for the fabrication of mechanically stable hydrogel materials with inherent functionalities in both hemostatic control and... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Soft Matter latest articles - Category: Chemistry Authors: Source Type: research
Many advances in healthcare have happened as a consequence of war; notable examples include in wound management, reconstructive or plastic surgery and in the use of helicopters to transport skilled care to the casualty and to reduce the time to receive...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news
Many advances in healthcare have happened as a consequence of war; notable examples include in wound management, reconstructive or plastic surgery and in the use of helicopters to transport skilled care to the casualty and to reduce the time to receive definitive care in specialist hospitals. Recent armed conflicts in Afghanistan and Iraq have helped to drive further understanding in the clinical management of post-traumatic stress disorder (PTSD) and of traumatic brain injury (TBI). However, even though art therapy had its origins in World War II relatively little is known about the true extent of the therapeutic benefits...
Source: Occupational Medicine - Category: Respiratory Medicine Source Type: research
CMS has implemented a new quality measure for hospitals that expands the array of pressure injuries considered as adversely impacting quality care.  The new measure, developed in a program to provide electronic clinical quality measures (eCQMs), widens the scope of pressure injury stages that directly infer quality deficit.  The new measure however, bears no consideration for unavoidability of some pressure injuries even when recommended clinical practice guidelines for prevention have been followed.  According to CMS, the benefit of eCQMs is to assess the outcomes of treatment, reduce the burden of manual a...
Source: Jeffrey M. Levine MD | Geriatric Specialist | Wound Care | Pressure Ulcers - Category: Geriatrics Authors: Tags: Featured Medical Articles Geriatric Medicine Pressure Injuries & Wound Care Risk Management bedsores decubiti decubitus ulcer end-of-life care geriatrics Healthcare Quality hospital quality Improving Medical Care Jeff Levine MD J Source Type: blogs
ConclusionSeverely anemic patients in critical condition can survive necrotizing fasciitis with a well-planned interdisciplinary approach without compromising patient autonomy.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
ConclusionThe CRU provides comprehensive Geriatrician led care for a wide variety of indications. This model of care offers a valid alternative to Emergency Department presentation and acute hospital admission.
Source: Age and Ageing - Category: Geriatrics Source Type: research
Chronic wound management is an enormous economic strain and quality-of-life issue for patients. Current treatments are ineffective or expensive and invasive. Materials (native and artificial) can act as the basis to enhance wound repair but often fall short of complete healing. The therapeutic index of materials have often been enhanced by combining them with drug or biologic elution technologies. Combination of materials with living drugs (cells) presents a new paradigm for enhancing therapy. Cell material interaction and therapeutic output will depend on variables ascribed to the living drug as well as variables ascribed...
Source: Mayo Clinic Proceedings - Category: Internal Medicine Authors: Tags: Review Source Type: research
Purpose of review Management of SSI comprises prevention, extensive diagnosis, and appropriate treatment as well as follow-up. All these are interrelated matters. This review gives a brief update on the latest developments in the field, specifically on new antibiotics that may find a place in this complex field. Recent findings Avibactam and dalbavancin are novel antiinfectives. Although randomized controlled trials in SSI are lacking to date, preliminary data show that new drugs may be alternatives to existing treatment. Currently, they should be used only on the ground of susceptibility testing, and if standard drug...
Source: Current Opinion in Infectious Diseases - Category: Infectious Diseases Tags: SPECIAL COMMENTARY: Edited by Matteo Bassetti Source Type: research
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