A Difficult-to-Treat Asthma Bronchiale Is Not Necessarily a Severe Asthma.

[A Difficult-to-Treat Asthma Bronchiale Is Not Necessarily a Severe Asthma]. Praxis (Bern 1994). 2019 Sep;108(11):715-721 Authors: Nussbaumer-Ochsner Y Abstract A Difficult-to-Treat Asthma Bronchiale Is Not Necessarily a Severe Asthma Abstract. New biologicals offer the opportunity for treatment of 'difficult-to-treat' asthma. Before prescribing these medications, each 'difficult-to-treat' asthma bronchiale has to be checked for factors aggravating asthma control (e.g. insufficient inhalation technique and adherence, persistent allergen exposure) and asthma-related comorbidities (e.g. rhinosinusitis, gastro-esophageal reflux disease or obstructive sleep apnea) rendering the asthma 'controlled'. Asthma phenotyping s essential for the understanding of different treatment modalities. PMID: 31480962 [PubMed - in process]
Source: Praxis - Category: General Medicine Authors: Tags: Praxis (Bern 1994) Source Type: research

Related Links:

We examined de-identified patient data from 28,508 unique encounters documented in the Asthma IQ database, obtaining patient level factors (demographics, asthma characteristics, co-morbidities), care setting (primary care physician [PCP] versus specialist physician [Allergist or Pulmonologist]), and guideline-defined levels of asthma control/severity. Rates of co-morbidities were identified by asthma severity and control and by care setting. We calculated odds ratios (ORs) for asthma control and severity based on each co-morbidity.ResultsBaseline demographic data indicated that patients seen by specialists versus PCPs, wer...
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Asthma affects approximately 300 million people worldwide and approximately 7.5% of adults in the United States. Asthma is characterized by inflammation of the airways, variable airflow obstruction, and bronchial hyperresponsiveness. The diagnosis of asthma is a clinical one with the history and physical examination being significant, but objective measures, such as pulmonary function testing, can be used to aid in the diagnosis. There are multiple associated comorbidities with asthma, including rhinitis, sinusitis, gastroesophageal reflux disease, obstructive sleep apnea, and depression. There is often an allergic compone...
Source: Medical Clinics of North America - Category: Primary Care Authors: Source Type: research
Conclusions:The absence of demographic or clinical predictors of OSA supports using general indications for PSG in children with ASD.Citation:Tomkies A, Johnson RF, Shah G, Caraballo M, Evans P, Mitchell RB. Obstructive sleep apnea in children with autism.J Clin Sleep Med. 2019;15(10):1469–1476.
Source: Journal of Clinical Sleep Medicine : JCSM - Category: Sleep Medicine Source Type: research
CONCLUSIONS: As with all cases of severe asthma, the assessment of comorbidities must be systematic in the presence of an occupational asthma which persists after the cessation of the occupational exposure. The management of these comorbidities can lead to an improvement in asthma control and severity. PMID: 31204233 [PubMed - as supplied by publisher]
Source: Revue des Maladies Respiratoires - Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research
This study utilized data from the annual, cross-sectional 2016 US National Health and Wellness Survey. Respondents self-reporting an OSA diagnosis were categorized as having ES (Epworth Sleepiness Scale [ESS] score≥ 11) or not having ES (ESS score
Source: Journal of Clinical Sleep Medicine : JCSM - Category: Sleep Medicine Source Type: research
Publication date: Available online 25 August 2018Source: Pulmonary Pharmacology &TherapeuticsAuthor(s): Luane Marques de Mello, Álvaro A. CruzAbstractThe prevalence of non-communicable chronic diseases has been on the rise and the co-occurrence of morbidities is becoming more common. Multimorbidities are found more frequently among women, those with a history of mental disorders, lower level of schooling, and unfavorable socioeconomic condition. Physical inactivity, smoking and obesity are also associated with multimorbidities. Its occurrence is directly related to the age, affecting the majority of the individu...
Source: Pulmonary Pharmacology and Therapeutics - Category: Respiratory Medicine Source Type: research
This study analyzed the characteristics of patients with suspected OSA from the European Sleep Apnea Database according to presence/absence of physician-diagnosed asthma. Cross-sectional data in 16,236 patients (29.1% female) referred for suspected OSA were analyzed according to occurrence of physician-diagnosed asthma for anthropometrics, OSA severity and sleepiness. Sleep structure was assessed in patients studied by polysomnography (i.e. 48% of the sample). The prevalence of physician-diagnosed asthma in the entire cohort was 4.8% (7.9% in women, 3.7% in men, p 
Source: Journal of Sleep Research - Category: Sleep Medicine Authors: Tags: J Sleep Res Source Type: research
This article reviews this relationship and provides recommendations for management. Keywords: Insomnia, sleep disorder, psychiatric disorder, depression, psychosis, schizophrenia, anxiety disorder Insomnia affects 25 million people in the United States annually and leads to an estimated $100 billion health care burden. Insomnia has also been shown to be a causal factor in other medical and psychiatric disorders, cognitive impairments, accidents, absenteeism, and reduced quality of life.1 The cost of not treating insomnia is more than the cost of treating insomnia.2 Insomnia as a symptom is seen in up to one third of the Un...
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Current Issue Review anxiety disorder depression insomnia psychiatric disorder psychosis schizophrenia sleep disorder Source Type: research
Conclusions: As compatible with previous research, we recognized asthma and PBB as the most frequent causes of chronic cough. We believe that implementation of a standardized algorithm including investigation of OSA as an etiological factor of chronic cough in children may improve clinical outcomes.Figure-1: Etiologies of patients (n=251)*: Three patients were diagnosed as astma and gastroesophageal reflux
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Epidemiology Source Type: research
Abstract Although chronic cough in adults (cough lasting longer than eight weeks) can be caused by many etiologies, four conditions account for most cases: upper airway cough syndrome, gastroesophageal reflux disease/laryngopharyngeal reflux disease, asthma, and nonasthmatic eosinophilic bronchitis. Patients should be evaluated clinically (with spirometry, if indicated), and empiric treatment should be initiated. Other potential causes include angiotensin-converting enzyme inhibitor use, environmental triggers, tobacco use, chronic obstructive pulmonary disease, and obstructive sleep apnea. Chest radiography can r...
Source: American Family Physician - Category: Primary Care Authors: Tags: Am Fam Physician Source Type: research
More News: Acid Reflux | Asthma | Gastroenterology | Gastroesophageal Reflux Disease | General Medicine | GERD | Obstructive Sleep Apnea | Sleep Apnea | Sleep Disorders | Sleep Medicine