A clinicopathological study of upper aerodigestive tract cancers

Conclusion: Studies are essential for education and awareness aimed at reducing exposure to habit-forming substances.
Source: Nigerian Journal of Clinical Practice - Category: Rural Health Authors: Source Type: research

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We report here a rare tri-allelic variant at the D8S1179 locus in a 6-month-old female child, observed during routine paternity testing in the Indian Tamil population.DNA eluted from the blood samples collected on FTA elute microcards were subjected to STR typing for autosomal and sex STR loci using the commercial AmpFlSTR Identifiler Plus kit and the Promega PowerPlex® Fusion kit. Capillary electrophoresis was carried out in ABI 3130xl Genetic Analyzer and genotyped using GeneMapper ID-X Software v1.5. Copy number variations and aneuploidy status of chromosome 8 were analyzed using Multiplex ligation-dependent probe a...
Source: Meta Gene - Category: Genetics & Stem Cells Source Type: research
Authors: PMID: 31977403 [PubMed - in process]
Source: The American Journal of Nursing - Category: Nursing Tags: Am J Nurs Source Type: research
ConclusionWe present the first risk score model to predict IGBC. The model estimates the expected risk for the individual patient and may help to optimize treatment strategies.
Source: The American Journal of Surgery - Category: Surgery Source Type: research
Authors: Zhang J, Si J, Gan L, Guo M, Yan J, Chen Y, Wang F, Xie Y, Wang Y, Zhang H Abstract Cervical cancer is the second most common malignant tumour threatening women's health. In recent years, heavy-ion beam therapy is becoming a newly emerging therapeutic mean of cancer; however, radio-resistance and radiation-induced damage constitute the main obstacles for curative treatment of cervical cancer. Therefore, to identify the radiosensitizers is essential. Here, we investigated the effects of Wnt signalling pathway on the response of 12C6+ radiation in HeLa cells. XAV939, an inhibitor of Wnt signalling pathway, w...
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
Publication date: Available online 24 January 2020Source: Seminars in Ultrasound, CT and MRIAuthor(s): Supreeta Arya, Saugata Sen, Reena Engineer, Avanish Saklani, Tarun PandeyAbstractHigh-resolution phased array external MRI is the first investigation of choice in rectal cancer for local staging, both in the primary and restaging situations. Use of MRI helps differentiate between those with good prognosis, which can be offered upfront surgery and the poor prognostic cases where treatment intensification is needed. MRI identified poor prognostic factors are threatened or involved mesorectal fascia, T3 tumors with> 5mm e...
Source: Seminars in Ultrasound, CT and MRI - Category: Radiology Source Type: research
Publication date: Available online 24 January 2020Source: Journal of Vascular and Interventional RadiologyAuthor(s): Yumei Yang, Yanfang Zhang, Yumin Wu, Jibing Chen, Bing Liang, Quanhong Chen, Qiuyu Wang, Jialing Lyu, Yong Li, Feng Mu, Duanming DuAbstractPurposeTo evaluate the efficacy and safety of percutaneous argon-helium cryoablation (CA) for hepatocellular carcinoma (HCC) abutting the diaphragm (
Source: Journal of Vascular and Interventional Radiology - Category: Radiology Source Type: research
Publication date: Available online 24 January 2020Source: Pathology - Research and PracticeAuthor(s): Xiaoyu Gao, Suhua Zhong, Yan Tong, Yushan Liang, Guofei Feng, Xiaoying Zhou, Zhe Zhang, Guangwu HuangAbstractCollagen (COL) genes participate in tumor extracellular matrix (ECM)-receptor interactions and focal adhesion pathways, which play a crucial role in tumor invasion and metastasis. The prognostic value of COL genes has been shown for several malignancies. In the present study, we analyzed multiple microarray datasets using the Oncomine database to identify alterations of COL genes in gastric cancer (GC). Gene express...
Source: Pathology Research and Practice - Category: Pathology Source Type: research
PANCREATIC cancer is when uncontrollable cells multiply within the pancreas. The large gland is part of the digestive system, and so warning signs of the deadly condition could be flushed away in the toilet bowl.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Publication date: Available online 24 January 2020Source: Microbial PathogenesisAuthor(s): Namita Singh, Priya Prasad, Banashree Das, Sangita RastogiAbstractCytokines might be involved in spontaneous abortion by triggering inflammatory mediators (Cyclooxygenases (Cox)) leading to spontaneous abortion in Chlamydia trachomatis (Ct)-infected women. Study aimed to quantitate the expression of pro-inflammatory cytokines (TNF-α, IFN-γ, IL-8) and Cox-2 in endometrial curettage tissue (ECT) of Spontaneous Aborters (SA). SA (n = 135) and 120 age-matched controls were enrolled from SJH, New Delhi, India. PCR was perf...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Publication date: Available online 24 January 2020Source: Microbial PathogenesisAuthor(s): Mani Divya, Marimuthu Govindarajan, Sivashanmugam Karthikeyan, Elumalai Preetham, Naiyf S. Alharbi, Shine Kadaikunnan, Jamal M. Khaled, Taghreed N. Almanaa, Baskaralingam VaseeharanAbstractβ-Glucan-binding protein (βGBP) is important for the rational expansion of molecular biology. Here, zinc oxide nanoparticle (ZnONP) was synthesized using βGBP from the crab Scylla serrata (Ss-βGBP-ZnONP). Ss-βGBP-ZnONP was observed as a 100 kDa band on sodium dodecyl sulfate polyacrylamide gel and characterized with UV&nd...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
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