Membrane Lipid Remodeling Takes Center Stage in Growth Factor Receptor-Driven Cancer Development.

Membrane Lipid Remodeling Takes Center Stage in Growth Factor Receptor-Driven Cancer Development. Cell Metab. 2019 Sep 03;30(3):407-408 Authors: Swinnen JV, Dehairs J, Talebi A Abstract Enhanced growth factor signaling is a hallmark of cancer, allowing cancer cells to thrive in a challenging environment. In this issue of Cell Metabolism, Bi et al. (2019) identify LPCAT1, a key membrane lipid remodeling enzyme, as a central link between genetically driven growth factor receptor expression, signaling, and tumor growth, highlighting lipid remodeling as a therapeutic target in cancer. PMID: 31484051 [PubMed - in process]
Source: Cell Metabolism - Category: Cytology Authors: Tags: Cell Metab Source Type: research