Dengue and chikungunya among outpatients with acute undifferentiated fever in Kinshasa, Democratic Republic of Congo: A cross-sectional study

DiscussionChikungunya outbreaks have been reported in the study area in the past, so the high seroprevalence is not surprising. However, scarce evidence exists on dengue transmission in Kinshasa and based on our data, circulation is more important than previously reported. Furthermore, our study shows that the prescription of antibiotics, both antibacterial and antimalarial drugs, is rampant. Studies like this one, elucidating the causes of acute fever, may lead to a more considerate and rigorous use of antibiotics. This will not only stem the ever-increasing problem of antimicrobial resistance, but will –ultimately and hopefully–improve the clinical care of outpatients in low-resource settings. Trial registrationClinicalTrials.gov NCT02656862.
Source: PLoS Neglected Tropical Diseases - Category: Tropical Medicine Authors: Source Type: research

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Source: MCN: The American Journal of Maternal Child Nursing - Category: Nursing Tags: ONGOING COLUMNS: Hot Topics in Maternity Nursing Source Type: research
[Premium Times] No fewer than 16,992 children below the age of five were treated of malaria under the EU/UNICEF Maternal, New-born and Child Health and Nutrition (MNCHN) project in Adamawa.
Source: AllAfrica News: Malaria - Category: Infectious Diseases Source Type: news
Publication date: Available online 9 December 2019Source: Fish &Shellfish ImmunologyAuthor(s): Qingchao Wang, Wei Ji, Zhen XuAbstractIn the past decades, the aquaculture industry made great progress in China, which contributes more than 70% yield of the world's farmed fish. Along with the rapid growth of fish production, increased emergence and outbreak of numbers of diseases pose harm to the aquaculture industry and food safety. From the efficient, safe, environmental and ethical aspects, vaccines is definitely the most appropriate and focused method to control different kinds of fish diseases. In China, researchers h...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
Recent occurrences of filoviruses and the arenavirus Lassa virus (LASV) in overlapping endemic areas of Africa highlight the need for a prophylactic vaccine that would confer protection against all of these viruses that cause lethal hemorrhagic fever (HF). We developed a quadrivalent formulation of VesiculoVax that contains recombinant vesicular stomatitis virus (rVSV) vectors expressing filovirus glycoproteins and that also contains a rVSV vector expressing the glycoprotein of a lineage IV strain of LASV. Cynomolgus macaques were vaccinated twice with the quadrivalent formulation, followed by challenge 28 days after the b...
Source: Journal of Clinical Investigation - Category: Biomedical Science Authors: Source Type: research
Conclusion: Our findings revealed that EL significantly reduced blood uric acid levels, prevented pathological changes of kidney in PO induced hyperuricemia animal model, and improved renal urate transports. We partly clarified the mechanism was related to suppressing effect of URAT1 by quassinoid in EL. This study is the first to demonstrate that EL plays a role in hyperuricemia by promoting renal uric acid excretion.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Over the past few decades, antimicrobial resistance has emerged as an important threat to public health due to the global dissemination of multidrug-resistant strains from several bacterial species. This worrisome trend, in addition to the paucity of new antibiotics with novel mechanisms of action in the development pipeline, warrants the development of non-antimicrobial approaches to combating infection caused by these isolates. Monoclonal antibodies (mAbs) have emerged as highly effective molecules for the treatment of multiple diseases. However, in spite of the fact that antibodies play an important role in protective i...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Resumo Este artigo avalia a rela ção de custos entre a saúde pública e a implementação do saneamento básico na capital da Guiné-Bissau. Analisaram-se seis cenários, incluindo três opções para o sistema de esgotamento sanitário (sistema coletivo com rede coletora e estação elevatória de esgoto, sistema simplificado i ndividual por latrina e sistema coletivo completo com rede coletora, estação elevatória e estação de tratamento de esgoto) e duas para o sistema de abastecimento de &...
Source: Saude e Sociedade - Category: International Medicine & Public Health Source Type: research
Resumo Este artigo avalia a rela ção de custos entre a saúde pública e a implementação do saneamento básico na capital da Guiné-Bissau. Analisaram-se seis cenários, incluindo três opções para o sistema de esgotamento sanitário (sistema coletivo com rede coletora e estação elevatória de esgoto, sistema simplificado i ndividual por latrina e sistema coletivo completo com rede coletora, estação elevatória e estação de tratamento de esgoto) e duas para o sistema de abastecimento de &...
Source: Saude e Sociedade - Category: International Medicine & Public Health Source Type: research
So far, 100 people have been sickened in 23 states and 58 people have been hospitalized in the current E. coli outbreak linked to romaine lettuce grown in Salinas, California, the CDC said last week
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
(Reuters Health) - Even with measles outbreaks common in many parts of the world, doctors and parents are often not opting to have children vaccinated before international travel, a new study suggests.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
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