Dengue and chikungunya among outpatients with acute undifferentiated fever in Kinshasa, Democratic Republic of Congo: A cross-sectional study
DiscussionChikungunya outbreaks have been reported in the study area in the past, so the high seroprevalence is not surprising. However, scarce evidence exists on dengue transmission in Kinshasa and based on our data, circulation is more important than previously reported. Furthermore, our study shows that the prescription of antibiotics, both antibacterial and antimalarial drugs, is rampant. Studies like this one, elucidating the causes of acute fever, may lead to a more considerate and rigorous use of antibiotics. This will not only stem the ever-increasing problem of antimicrobial resistance, but will –ultimately and hopefully–improve the clinical care of outpatients in low-resource settings. Trial registrationClinicalTrials.gov NCT02656862.
CONCLUSION: Prevalence of antibiotic use was high not only versus other hospitals in the region but globally including Africa, coupled with significant evidence of sub-optimal prescribing. Swift action is needed to improve future prescribing to reduce AMR. One or two areas should initially be targeted for quality improvement including development of local guidelines, documentation of antibiotic indications and/or stop/review dates. PMID: 33034234 [PubMed - as supplied by publisher]
Publication date: Available online 10 October 2020Source: Journal of Genetics and GenomicsAuthor(s): Chengqi Wang, Justin Gibbons, Swamy R. Adapa, Jenna Oberstaller, Xiangyun Liao, Min Zhang, John H. Adams, Rays H.Y. Jiang
Publication date: Available online 9 October 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Manuel Jorge Rial, Marcela Valverde, Victoria del Pozo, Francisco Javier González-Barcala, Carlos Martínez-Rivera, Xavier Muñoz, José María Olaguibel, Vicente Plaza, Elena Curto, Santiago Quirce, Pilar Barranco, Javier Domínguez-Ortega, Joaquin Mullol, César Picado, Antonio Valero, Irina Bobolea, Ebymar Arismendi, Paula Ribó, Joaquín Sastre
Conclusion: This study demonstrates that the crude extract of A. hispidum DC, one of the plants used traditionally to treat malaria, inhibits the growth of P. falciparum in vitro and could be a potential source of antimalarial drug. The report has highlighted genotoxic and cytotoxic effects of the selected plant extracts on human leukocytes as well. PMID: 33029160 [PubMed]
Trump plans in-person rally on Monday as next presidential debate cancelled; Europe records 100,000 daily cases for first time; Canada at ‘tipping point’. Follow latest updatesEurope: Spain declares emergency in Madrid as Berlin emerges as hotspotUK workers to get two-thirds of wages if firms told to shutAustralia: Is Victoria ready to come out of lockdown?US presidential debate cancelled – live updatesSee all our coronavirus coverage5.42amBSTMy colleagueLuke Henriques-Gomes has this story giving you a summary of the main Covid-19 stories from Australia.A main point of the day has beenVictoria ’s pr...
Publication date: Available online 9 October 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): Elma L. Leite, Wydemberg J. Araújo, Tatiana R. Vieira, Karoline S. Zenato, Priscylla C. Vasconcelos, Samuel Cibulski, Patricia E.N. Givisiez, Marisa R.I. Cardoso, Celso J.B. Oliveira
Publication date: Available online 8 October 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): E.L. Looman, P. van Tienen, D.Y.K. Ng, S. Baig, A. Fait, S. Overballe-Petersen, P.S. Andersen, M. Stegger
AbstractThere are several different types of sources responsible for the emissions of carbon monoxide (CO), sulphur dioxide (SO2), nitrogen dioxide (NO2) and aerosols in Africa. These emissions make the African continent vulnerable to the impacts on climate change, human health and the environment. It has been shown that the southern African emissions are dominant in the winter season (JJA). However, few studies have been done to study the winter and spring season in unison to understand these emissions. Therefore, in this study, both satellite data, such as Sentinel-5P and the Cloud-Aerosol Lidar and Infrared Pathfinder S...
WHO emergencies chiefwarns ‘there are no new answers’ as cases surge globally. This blog has now closed. Follow our latest blog belowCoronavirus – latest updates12.58amBSTWe are closing this live blog now, but you can stay up to date on all the latest news, including a press conference from Victoria at 11am, hosted by Daniel Andrews, on our new blog below:Related:Coronavirus live news: France sets daily record 20,000 cases; Australian state of Victoria reports 14 new infections12.43amBSTI ’ve just got some clarification on the “positive test result” reported for Goodna, near Ipswich, wes...
The coronavirus outbreak has indelibly imprinted itself on life in Los Angeles — down to the composition of trash washing up on its beaches.