Proteomics in gastroparesis: Unique and overlapping protein signatures in diabetic and idiopathic gastroparesis.

CONCLUSIONS: Protein expression changes suggest a central role of macrophage-driven immune dysregulation in gastroparesis; specifically, complement activation in diabetic gastroparesis.
PMID: 31482734 [PubMed - as supplied by publisher]

Source: American Journal of Physiology. Gastrointestinal and Liver Physiology - September 3, 2019 Category: Physiology Authors: Grover M, Dasari S, Bernard CE, Chikkamenahalli LL, Yates KP, Pasricha PJ, Sarosiek I, McCallum RW, Koch KL, Abell TL, Kuo B, Shulman RJ, Gibbons SJ, McKenzie TJ, Kellogg TA, Kendrick ML, Tonascia J, Hamilton FA, Parkman HP, Farrugia G, Gastroparesis Clin Tags: Am J Physiol Gastrointest Liver Physiol Source Type: research