Sensors, Vol. 19, Pages 3839: Cuvette-Type LSPR Sensor for Highly Sensitive Detection of Melamine in Infant Formulas

Sensors, Vol. 19, Pages 3839: Cuvette-Type LSPR Sensor for Highly Sensitive Detection of Melamine in Infant Formulas Sensors doi: 10.3390/s19183839 Authors: Seo Yeong Oh Min Ji Lee Nam Su Heo Suji Kim Jeong Su Oh Yuseon Lee Eun Jeong Jeon Hyungsil Moon Hyung Soo Kim Tae Jung Park Guiim Moon Hyang Sook Chun Yun Suk Huh The globalization of food distribution has made necessary to secure safe products to the general consumers through the rapid detection of harmful additives on the field. For this purpose, we developed a cuvette-type localized surface plasmon resonance (LSPR) sensor that can be easily used by consumers with conventional ultraviolet-visible light spectrophotometer for in-situ measurements. Gold nanoparticles were uniformly deposited on a transparent substrate via a self-assembly method to obtain a plasmonically active chip, and the chemical receptor p-nitroaniline (p-NA) was functionalized to stabilize the device sensitivity under external temperature and pH conditions. The fabricated chip was fixed onto a support and combined with a cuvette-type LSPR sensor. To evaluate the applicability of this sensor on the field, sensitivity and quantitative analysis experiments were conducted onto melamine as a model sample from harmful food additives. Under optimal reaction condition (2 mM p-NA for 20 min), we achieved an excellent detection limit (0.01 ppb) and a dynamic range allowing quantitative analysis over a wide concentration range (0....
Source: Sensors - Category: Biotechnology Authors: Tags: Article Source Type: research