A new drug for low sexual desire in women: Bremelanotide

Women who feel distressed by a lack of sexual desire may have some help on the way. Recently the FDA approved bremelanotide (Vyleesi), a new medication for premenopausal women with hypoactive sexual desire disorder (HSDD). HSDD is a term coined to describe low sexual desire without a clear cause. So, women who might like to try this new drug need to know that it is not intended to help in situations where desire diminishes due to a medical or psychiatric illness interpersonal or relationship problems side effects from another treatment or medication. What does research tell us? The physiology of sexual arousal and desire is complex in women. Yet there’s not a lot of research in this area. An estimated 40% of women are affected by a lack of desire for sex. The numbers vary depending on what age women are, where they live, and whether they have recently given birth, but there’s no doubt that it is a significant problem for some women. In research funded by a licensing partner of the drug manufacturer, bremelanotide was studied for both effectiveness and safety. According to information released by the FDA, more than 1,200 women randomly received either bremelanotide or a placebo (sham treatment) for up to 24 weeks. About 25% of the women who took bremelanotide reported some increase in sexual desire compared with 17% of those who took a placebo. The research also looked at the women’s distress over low sexual desire. About 35% of the patients treated wi...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Relationships Sex Women's Health Source Type: blogs

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CONCLUSIONS Ministry of Health policies on the amount of patient cost sharing and on the choice of medicines on coverage lists have substantial impacts on overall generic sales volume in retail pharmacies.
Source: Revista de Saude Publica - Category: International Medicine & Public Health Source Type: research
The purpose of this paper is twofold: first, to argue that substance use is a real risk for people who experience disaster, and especially so for socially vulnerable populations; second, to incorporate questions that help measure substance use during the d...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
This research investigates the source of Black-White differences in drug arrests by conducting a neighborhood-level test of the differential police scrutiny and racially discriminatory policing hypotheses. The study examines drug arrests made across 78 nei...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
This article estimates the relationship between alcohol outlets and crime at micro place street units in Washington, D.C. The analysis tests several spatial hypotheses on the local and spatial diffusion effects of on-premise and off-premise alcohol outlets...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
Publication date: Available online 16 October 2019Source: Pharmacological ResearchAuthor(s): Sivakkanan Loganathan, Yuxing Guo, Weipeng Jiang, Tamás Radovits, Mihály Ruppert, Alex Ali Sayour, Maik Brune, Paige Brlecic, Phillipp Gude, Adrian-Iustin Georgevici, Benito Yard, Matthias Karck, Sevil Korkmaz-Icöz, Gábor SzabóAbstractThe major source of heart transplantation comes from brain-dead (BD) donors. However, brain death and myocardial ischemia/reperfusion injury during transplantation may lead to cardiac dysfunction and hemodynamic instability. A previous work demonstrated that pre-treatm...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
ConclusionThe anti-inflammatory effects of X. aethiopica leaves are demonstrated experimentally, thus substantiating its use in folk Medicine. Relevantly, the observed anti-inflammatory properties can stimulate further studies in order to fully unveil the therapeutic potential of the plant, namely as sources of phenolic compounds with a significant ability to interfere with conventional inflammatory targets.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
CONCLUSIONS Pulmonary hypertension occurred in 25% of the 182 interstitial lung disease patients and was negatively associated with deteriorated lung functions (specifically VC%, FVC%, and DLCO parameters). ANA level was not associated with the prognosis of pulmonary hypertension of patients with interstitial lung disease, and it did not significantly affect the correlation between PASP and pulmonary functions. Thus, ANA level did not seem to be a necessary indicator of pulmonary hypertension, and a more effective treatment method for pulmonary hypertension of patients with interstitial lung disease is urgently needed. ...
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
ConclusionThis study showed that calcitonin could be helpful analgesic agent in different painful situations. Calcitonin can be considered an eligible treatment for acute pains related to vertebral fractures and a feasible alternative for the treatment of the acute and chronic neuropathic pains where other medications might fail.ResumoJustificativa e objetivosA calcitonina é um hormônio polipeptídico que regula o metabolismo do cálcio no organismo. Por muitos anos a calcitonina tem sido usada para manter e melhorar a densidade mineral óssea e reduzir a incidência de fraturas. Muitos ...
Source: Brazilian Journal of Anesthesiology - Category: Anesthesiology Source Type: research
Publication date: Available online 16 October 2019Source: Neuroscience LettersAuthor(s): Jie Cheng, Fan Li, Xiaoming Sun, Shuqin Liu, Lina Chen, Feng Tian, Zhenghang Zhao, Hao Hu, Xiaogang LiAbstractRecent studies showed that homocysteine (Hcy) levels were obviously elevated in patients with anxiety, furthermore, oxidative stress and inflammation were closely linked with Hcy-related damage. Despite alcohol exposure has differential effects on different forms of anxiety, the role of alcohol on anxiety-related behavior induced by high Hcy levels is still not entirely clear. The present study investigated the protective poten...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
Publication date: Available online 16 October 2019Source: Journal of Clinical NeuroscienceAuthor(s): Na Qu, Shu-Fang Zhang, Bin Xia, Jia-Zhao Xie, Xiao-Ming Wang, Jun Liu, Jie Xiong, Na Ren, Yan Wang, Qing Tian, Yi LiAbstractCognitive dysfunction and pro-inflammatory effect has been associated with major depressive disorder (MDD), but sex differences have seldom been studied. The study was to determine the sex difference of cognitive dysfunction and pro-inflammatory biomarkers among patients with MDD in Chinese Han population. 104 MDD patients (male n = 37, female n = 67) were included in the study. Their sociodemo...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
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