Screenings for lung cancer can point to other smoking-related conditions

About 77 percent of patients who received CT scans for lung cancer were diagnosed with cardiovascular disease, emphysema or osteoporosis, according to a new study showing the same scan can screen for additional diseases.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news

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Authors: Xu W, Lou Y, Chen W, Kang Y Abstract Effective cancer therapy usually requires the assistance of well-designed drug carriers. In order to increase the drug accumulation to tumor tissue as well as to reduce the side effects of drug carriers, the hybrid drug delivery system (DDS) was developed by integrating folic acid (FA) and a metal-organic framework (MOF). The anticancer drug doxorubicin (DOX) was preloaded into the MOF nanoparticles during the synthesis process of the MOF nanoparticles. After surface modification with FA, the resulting FA/MOF/DOX nanoparticles were capable of serving as a biocompatible ...
Source: Biomedizinische Technik/Biomedical Engineering - Category: Biomedical Engineering Tags: Biomed Tech (Berl) Source Type: research
What are the latest strategies for fertility preservation in adolescent and young adult survivors of childhood cancer?Current Opinion in Urology
Source: Medscape Transplantation Headlines - Category: Transplant Surgery Tags: Urology Journal Article Source Type: news
Publication date: Available online 12 October 2019Source: The Journal of Steroid Biochemistry and Molecular BiologyAuthor(s): Alexandra Kollara, Premalatha Shathasivam, Soyeon Park, Maurice J. Ringuette, Theodore J. BrownAbstractStudies indicate androgens contribute to initiation or progression of epithelial ovarian cancer through poorly understood mechanisms. We provide evidence that the androgen receptor (AR) interacts in a ligand-independent manner with the putative armadillo repeat domain of ventricular zone expressed PH domain-containing 1 (VEPH1). This interaction was increased by mutation of the two nuclear receptor...
Source: The Journal of Steroid Biochemistry and Molecular Biology - Category: Biochemistry Source Type: research
This article reviews the major pathways by which adrenal steroids are converted to the potent male sex hormones, testosterone (T) and 5α-dihydrotestosterone (5α-DHT) and the discrete enzyme isoforms involved in castration resistant prostate cancer. Previous studies have mainly utilized radiotracers to investigate these pathways but have not used prevailing concentrations of precursors found in castrate male human serum. In addition, the full power of stable-isotope dilution liquid chromatography tandem mass spectrometry has not been applied routinely. Furthermore, it is clear that adaptive responses occur in th...
Source: The Journal of Steroid Biochemistry and Molecular Biology - Category: Biochemistry Source Type: research
Publication date: Available online 12 October 2019Source: The Journal of Steroid Biochemistry and Molecular BiologyAuthor(s): Laura Tatiana Pelegrina, Myriam LaconiAbstractOvarian carcinoma is one of the most common cause of death by gynecologic cancer. Several epidemiological and in vitro studies have shown controversial data about progesterone effects in ovarian cancer. Progesterone can be converted in its active metabolite, allopregnanolone, its effects in ovarian cancer are still unknown. Previously, we demonstrated that allopregnanolone modifies ovarian morphophysiology, being able to alter critical process of tumor d...
Source: The Journal of Steroid Biochemistry and Molecular Biology - Category: Biochemistry Source Type: research
Publication date: Available online 12 October 2019Source: Sensors and Actuators B: ChemicalAuthor(s): C. Busacca, A. Donato, M. Lo Faro, A. Malara, G. Neri, S. TrocinoAbstractCobalt oxide (Co3O4) nanostructures are synthesized by the electrospinning method and their performances as CO gas sensor are investigated. Ethanol (EtOH) and N,N-Dimethylformamide (DMF) are selected as solvents to be separately mixed with cobalt(II) nitrate hexahydrate (Co(NO3)2·6H2O) and polyvinylpyrrolidone (PVP) in order to obtain two different solutions for the electrospinning and consequently two different morphologies of the electrospun ...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
THURSDAY, Sept. 12, 2019 -- CT lung cancer screening can detect other serious smoking-related conditions, such as heart disease, osteoporosis and emphysema, researchers say. Medical experts consider lung cancer screening an effective way to detect...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
New diagnoses of CVD, emphysema, osteoporosis identified, often are linked to adverse events
Source: Pulmonary Medicine News - Doctors Lounge - Category: Respiratory Medicine Tags: Cardiology, Endocrinology, Family Medicine, Geriatrics, Internal Medicine, Oncology, Orthopedics, Pulmonology, Radiology, Rheumatology, Journal, Source Type: news
This study affirms that these people can experience serious health consequences, even without COPD. This finding also brings into question how we should classify chronic respiratory disease. So far, we haven’t determined a way of classifying those who have symptoms but don’t quite meet the usual criteria for COPD, and we also don’t have much data or guidance on how best to treat them. In the meantime, quitting smoking remains the best way to lower your chances of getting COPD — and the best way to lessen any respiratory symptoms you’re having. Most smokers who stop will feel better, with less ...
Source: New Harvard Health Information - Category: Consumer Health News Authors: Tags: Health Lung disease Smoking cessation COPD Source Type: news
Conclusions: Bone density is lower with increasing extents of emphysema and small airway disease, but is not associated with large airway disease and trachea deformity. This may indicate the necessity to measure bone density early in the disease in COPD patients with emphysema and air trapping to prevent vertebral fractures.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: 1.3 Imaging Source Type: research
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